Safely Buy Evamist ( Estradiol ) from Canada Prescriptions Plus.

Indications

Evamist is a prescription medication used to treat moderate-to-severe vasomotor symptoms (such as hot flashes) due to menopause.

Evamist is a transdermal spray that contains estradiol, an estrogen hormone that is absorbed through the skin and enters into the bloodstream.

Use and Dosage

Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. Learn how to use the spray correctly. If you have any questions, ask your doctor or pharmacist.

Follow the instructions for priming the spray if you are using it for the first time.

Keep the spray upright when using. Spray this medication on clean, dry skin of the inside area of your forearm (between the elbow and the wrist) as directed by your doctor, usually once daily in the morning. If your dose is for more than 1 spray, do not use more than 1 spray on the same area of the skin. The application sites should be next to each other but not overlapping. Avoid applying this medication to broken, irritated skin. Do not apply this medication to other areas of the body, including the breast, face, or in or around the vagina.

The dosage is based on your medical condition and response to treatment. Do not increase your dose or use this medication more often than prescribed.

Replace the cap on the spray after each use. After applying this medication, wash your hands thoroughly with soap and water. Wait at least 2 minutes for the application site to dry completely before dressing. Do not rub the medication on the skin. Cover the application site with clothing (such as a long-sleeve shirt) to prevent others from touching the application area and being exposed to the drug. If someone accidentally touches the application site, have them wash the area of contact on their body with soap and water as soon as possible. Also, keep pets from coming into contact with the application site.

To get the best effect, wait at least 1 hour before washing the application site to allow the drug to be absorbed through the skin.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

Avoid getting this medication in the eyes. If this medication gets in the eyes, rinse them right away with warm water. Tell your doctor if you get any eye irritation.

This medication is flammable until dry. Let the medication dry before smoking or going near an open flame.

Keep track of the number of sprays you use. Discard the container after you have used the labelled number of sprays on the product package, even if there is medication left in the container.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to Evamist: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Evamist and call your doctor at once if you have:

• Heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, or sweating
• Signs of a blood clot – sudden numbness or weakness, sudden vision loss, slurred speech, stabbing chest pain, coughing up blood, or pain or warmth in one or both legs
• Swelling or tenderness in your stomach, severe stomach pain spreading to your back, or nausea and vomiting
• Jaundice (yellowing of the skin or eyes)
• Memory problems, confusion, or unusual behavior
• Unusual vaginal bleeding or pelvic pain
• A lump in your breast
• High calcium levels – confusion, tiredness, nausea, vomiting, loss of appetite, constipation, increased thirst or urination, or weight loss

Topical estradiol is absorbed through the skin of a child who comes into contact with this medicine. Call your doctor if a child who has close contact with you develops swollen nipples or enlarged breasts.

Common Evamist side effects may include:

• Breast pain
• Headache
• Vaginal itching or discharge, changes in your menstrual periods, or light vaginal bleeding or spotting
• Thinning scalp hair
• Nausea, vomiting, bloating, or stomach cramps

This is not a complete list of side effects and others may occur.

Cautions

Before using estradiol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, mental/mood disorders (such as dementia, depression), a certain blood disorder (porphyria).

Do not smoke or use tobacco. Estrogens combined with smoking further increase your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35.

Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are using an estrogen product. You may need to stop this medication for a time or take special precautions.

This drug may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Wear protective clothing when outdoors. Ask your doctor or pharmacist about using sunscreen with this medication. Sunscreen may affect this medication’s absorption if applied to the area of the skin where it was applied.

If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur.

This product is not meant for children. See the Warning section about the risks to children if they are accidentally exposed to this medication.

This medication should not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away.

This medication passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breastfeeding.

Form and Strengths

Evamist is available in the following form and strengths:

• Evamist Spray Pump:
  • 1.53 mg

FAQ

What happens if I miss a dose?

Use the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not use extra medicine to make up for the missed dose.

What happens if I overdose?

Seek emergency medical attention. Overdose symptoms may include nausea, vomiting, stomach pain, breast tenderness, drowsiness, and vaginal bleeding.

What should I avoid while using Evamist?

Avoid getting Evamist in your eyes. If this does happen, rinse with water.

Wait at least 25 minutes after applying Evamist before you apply sunscreen to the same skin area.

Grapefruit and grapefruit juice may interact with estradiol and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

Resources:

1. https://www.webmd.com/drugs/2/drug-150030/evamist-transdermal/details
2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022014s001lbl.pdf
3. https://www.drugs.com/evamist.html#side-effects