Safely Buy Arthrotec ( Diclofenac/Misoprostal ) from Canada Prescriptions Plus.

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Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Arthrotec 50mg/200mcg 180 $204.00 Add To Cart
Arthrotec 75mg/200mcg 180 $254.52 Add To Cart
Dosage: 50mg/200mcg
Quantity: 180
Price: $204.00
Dosage: 75mg/200mcg
Quantity: 180
Price: $254.52


Arthrotec is a prescription medication used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis in adult patients at high risk for developing nonsteroidal anti-inflammatory drug (NSAID)-induced gastric and duodenal ulcers.

Arthrotec contains a combination of two active ingredients: diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID), and misoprostol, a synthetic prostaglandin E1 analog. The diclofenac sodium component helps reduce pain, swelling, and joint stiffness from arthritis, while the misoprostol component helps protect the stomach lining from potential damage caused by NSAIDs.

Arthrotec should not be used in women of childbearing potential unless the patient requires NSAID therapy and is at high risk for developing gastrointestinal complications.

Use and Dosage

Read the Medication Guide provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with a full glass of water (8 ounces/240 millilitres) unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking this medication.

Swallow the tablets whole. Do not crush, chew, or dissolve the tablets. Doing so can increase the risk of side effects. Do not take tablets that are broken.

Take this medication with food to prevent stomach upset and reduce the chances of diarrhea. Avoid taking antacids that contain magnesium while using this medication because they may worsen diarrhea. If you need an antacid, consult your doctor or pharmacist to help you choose a product.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time. Do not increase your dose or use this drug more often or for longer than prescribed. For ongoing conditions such as arthritis, keep taking this medication as directed. Discuss the risks and benefits with your doctor or pharmacist.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It may take up to 2 weeks of taking this drug regularly before you get the full benefit.

Tell your doctor if your condition does not get better or if it gets worse.

Side Effects

Common side effects:

  • Nausea
  • Dizziness
  • Headache
  • Drowsiness
  • Heartburn
  • Gas
  • Bloating

Mostly, the side effects caused by Arthrotec are mild and will resolve even without intervention. If the adverse reactions persist or get worse, you should hold the drug and consult your doctor or any health care professional.

Adverse reactions include:

  • High blood pressure or hypertension
  • Severe diarrhea
  • Dehydration
  • Palpitations
  • Painful swallowing
  • Ringing in the ears
  • Easy bruising or bleeding
  • Irregular periods
  • Unexplained stiff neck
  • Seizures
  • Changes in urine output
  • Symptoms of heart failure (shortness of breath, unusual tiredness, sudden weight gain, swelling of the lower extremities)
  • Signs of liver disease (severe abdominal pain, dark urine, yellowish eyes and skin, persistent vomiting)

This is not a complete list of Arthrotec’s side effects.


Before using this oral medication, you must disclose your complete medical history with your physician, especially stroke, blood disorders, clotting problems, gastrointestinal problems, liver disease, heart disease, hypertension, aspirin-sensitive asthma, and swelling. Certain diseases and disorders may affect how your body will respond to this drug. Furthermore, you must talk about all the prescription drugs and nonprescription drugs you are using because of possible drug interactions.

Continually watch out for an allergic reaction while on this treatment. Do not take this oral drug if you have a known allergy to diclofenac, misoprostol, other aspirin or NSAIDs, and any inactive ingredients each tablet may contain. Call your local emergency line once you notice signs of hypersensitivity, such as hives, swelling of the face, severe dizziness, skin rashes, and breathing trouble.

This type of medication may cause kidney problems. This condition could further be triggered by dehydration and heart failure. To avoid dehydration, avoid using diuretics and drink enough fluids.

Do not smoke or drink alcoholic beverages while taking this drug. Some substances from alcohol and tobacco could interact with Arthrotec and cause stomach bleeding. Alcohol could also worsen side effects, such as dizziness and drowsiness.

You could be more sensitive to the sun while on this treatment. Limit your sun exposure and avoid indoor tanning. You must also apply sunblock cream and wear protective clothing when going outdoors.

This drug could cause harm to pregnant moms and unborn babies. With this, you must not use this drug during pregnancy. On the other hand, it is unlikely to cause harm to breastfeeding moms and breastfed children.

Form and Strengths

Arthrotec is available in the following form and strengths:

Arthrotec Tablet:

  • 50/200 g
  • 75/200 mg


How often should I take this medication?

Your doctor may prescribe this drug twice or thrice daily.

How long will it take for this medication to work?

You may notice improvements in your signs and symptoms within two weeks of taking this drug.

Does this medication make you sleepy?

Drowsiness is among the adverse effects of this drug.



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50mg/200mcg, 75mg/200mcg

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