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Zebeta is a blood pressure medication used to treat hypertension (high blood pressure).

Bisoprolol is a beta blocker medication that inhibits the action of epinephrine and other chemicals in your body on your heart and blood vessels. These inhibitory actions allow Zebeta to reduce your heart rate, blood pressure, and heart strain to improve your hypertensive condition.

Dosage and Administration

The dose of Zebeta that is prescribed will vary depending on the individual being treated. Follow all your healthcare provider’s directions and read packaging labels carefully to ensure the best response during treatment. Do not change your dose of Zebeta on your own.

  • Swallow tablets whole
  • Take with or without food at the same time each day
  • Most adults start by taking 5mg once daily
  • Doses can gradually increase to 10mg once a day if needed
  • Adults should not take more than 20mg daily
  • Patients with impaired kidney or liver function should start by taking 2.5mg once daily and then increasing gradually if needed and tolerated
  • Zebeta may take several weeks to provide its full antihypertensive effects
  • Tell your healthcare provider if your condition worsens or does not improve
  • Continue taking Zebeta as prescribed even if you feel well
  • Store at room temperature away from children and pets

Side Effects

Zebeta may cause you to develop some side effects while affecting your cardiovascular system. Speak with your healthcare provider to learn more about any symptoms that you may have during treatment.

Common Zebeta side effects:

  • Headache
  • Tiredness
  • Insomnia
  • Joint pain
  • Swelling
  • Cold symptoms (stuffy nose, runny nose, cough, sore throat)

Serious Side Effects

Some more serious adverse effects may occur during treatment with Zebeta. Contact your healthcare provider immediately if you notice any of the following symptoms:

  • Shortness of breath, swelling, rapid weight gain
  • Slowed heart rate
  • Pounding heart or fluttering sensation in your chest
  • Numbness, tingling, cold feeling hands or feet
  • Light-headedness, feeling faint
  • Eye pain, problems with your vision
  • Bronchospasms (wheezing, tightness in your chest, difficulty breathing)

Allergic Reactions

Do not take Zebeta if you are allergic to bisoprolol. Stop using this medication and call your healthcare provider if you notice any of the following signs of an allergic reaction:

  • Hives
  • Trouble breathing
  • Swollen face, lips, tongue, or throat


  • Do not use Zebeta if you have a serious heart condition including AV block, severe heart failure, or slow heartbeats that cause you to faint.
  • To ensure your safety when using Zebeta, tell your healthcare provider if you have ever had any of the following conditions:
    • Congestive heart failure or other heart problems
    • Coronary artery disease
    • Problems with your circulation
    • Breathing problems like asthma or chronic obstructive pulmonary disease
    • Liver or kidney disease
    • Thyroid disorder
    • Diabetes
    • History of allergies
  • Tell your healthcare provider if you are pregnant or plan to become pregnant during treatment. It is unclear how this medication may affect you or your child if used during pregnancy.
  • Consult with your healthcare provider before breastfeeding while taking Zebeta. The medication may or may not pass into breastmilk and affect your nursing child.
  • Avoid drinking alcohol while taking Zebeta because it can increase the occurrence of adverse effects.
  • Be careful when driving or performing tasks that require alertness, especially until you know how this medication will affect you. Zebeta may impair your thinking or reactions; if this is the case then you should avoid these activities.
  • Move slowly when standing from a seated or laying position to avoid becoming dizzy.
  • Some drugs may interact with Zebeta and cause adverse reactions. Tell your healthcare provider about all the medications you take, including over the counter medicine, but especially any of the following:
    • Fingolimod
    • Insulin or oral diabetes medications
    • Rifampin
    • Other heart or blood pressure medications (clonidine, digitalis, digoxin, and others)
  • Zebeta is not an approved treatment method for anyone who is younger than 18.

Form and Strength

This antihypertensive medicine is available in tablet form.

  • Zebeta tablet strengths:
    • 2.5mg
    • 5mg
    • 10mg

The 2.5 and 10mg Zebeta tablets are both available in quantities of 84 while the 5mg tablets are available in groups of 30, 90, and 100 and the 10mg tablets are also available in quantities of 90.


What should I avoid when taking Zebeta?

During treatment with Zebeta you should avoid drinking alcohol, especially in high quantities, because it can cause the medication to lower your blood pressure to dangerous levels. This can increase side effects including dizziness and feeling faint. You should also avoid driving or performing hazardous tasks until you know how this medication will affect you and if your reactions are impaired.

Is it better to take Zebeta in the morning or at night?

Zebeta can be taken at any time of day without losing its effectiveness at lowering your blood pressure. However, your healthcare provider may recommend that you take your daily dose in the morning. If you experience dizziness from taking your doses, your healthcare provider may prescribe that you take your dose at night to minimize side effects. Follow all directions given by your healthcare provider for the best results during treatment.



Additional information

Brand Name:


Scientific Name:

Bisoprolol, Bisoprolol Fumarate

Other Names:

Bisoprolol, Concor


2.5mg, 5mg, 10mg

Quantities Available:

30, 84, 90, 100