Safely Buy Synjardy XR ( Empagliflozin/Metfromin hcl ) from Canada Prescriptions Plus.

Indications

Synjardy XR is a blood sugar medication used to treat type 2 diabetes mellitus and lower the risk of death from a heart attack, stroke, or heart failure in those who have heart disease as well as type 2 diabetes.

This diabetes medication combines empagliflozin, an SGLT2 inhibitor, with metformin, a biguanide, to help lower your blood sugar levels. Empagliflozin promotes the excretion of glucose through your urine to lower levels while metformin decreases the amount of glucose your liver produces and reduces the amount of sugar that is absorbed into your blood after eating meals.

The metformin in Synjardy XR also supports the absorption of glucose from your blood to help prevent it from building into plaque in your blood vessels which can lead to cardiovascular issues.

Dosage and Administration

The dose of Synjardy XR that is prescribed will vary depending on the individual being treated. Follow all your healthcare provider’s instructions and read packaging labels carefully to ensure the best results during treatment.

• Swallow tablets whole, do not crush or chew
• Take with food in the morning
• Most adults take 10mg of empagliflozin once daily
• If needed, doses can increase to a maximum of 25mg of empagliflozin
• Do not take more than 25mg of empagliflozin and 2,000mg of metformin each day

How to switch from other blood sugar medications:

• When taking metformin, start taking Synjardy XR with a similar total daily dosage of metformin and 10mg of empagliflozin
• When switching from empagliflozin, start taking Synjardy XR at a similar daily dosage with 1,000mg of metformin
• If you are currently taking both empagliflozin and metformin, start taking Synjardy XR with the same total daily doses of each drug

Side Effects

Synjardy XR may cause some side effects to develop while lowering and managing your blood sugar levels. Speak with your healthcare provider to learn more about any symptoms that you might encounter when taking Synjardy.

Common Synjardy XR side effects:

• Low blood sugar
• Indigestion, stomach pain, gas, nausea
• Vomiting, diarrhea
• Bladder infection
• Yeast infection (itching or unusual discharge)
• Headache, weakness
• Runny nose, sore throat

Serious Side Effects

Some more serious adverse reactions may occur during treatment with Synjardy XR. Stop using this diabetes medication and contact your healthcare provider right away if you develop any of the following symptoms:

• Light-headedness, feeling faint
• Dehydration (dizziness, confusion, feeling thirsty, less urination)
• Ketoacidosis (nausea, vomiting, stomach pain, confusion, unusual drowsiness, trouble breathing)
• Lactic acidosis (unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, feeling weak or tired)
• Signs of a bladder infection (pain or burning during urination, blood in your urine, pain in your pelvis or back)

Seek immediate medical attention if you develop any signs of a serious genital infection. Symptoms include burning, itching, odour, unusual discharge, pain, tenderness, redness, or swelling in the genital or rectal area, fever, general ill-feeling.

Allergic Reactions

Do not take Synjardy XR if you are allergic to empagliflozin, metformin, or any of the other tablet ingredients. If you notice any signs of an allergic reaction, stop taking this medication and call your healthcare provider.

Synjardy XR allergy symptoms may include:

• Hives
• Trouble swallowing
• Difficulty breathing
• Swelling of face, lips, tongue, or throat

Cautions

Synjardy XR is designed to lower blood sugar levels to treat type 2 diabetes; do not use this medication if you have type 1 diabetes.

Do not take Synjardy XR if you have any of the following:

• Severe kidney disease or if you are on dialysis
• Metabolic acidosis
• Diabetic ketoacidosis

You may need to temporarily stop taking Synjardy if you undergo a surgery or scan that uses injected dye. Tell anyone who treats you that you take this medication.

To ensure your safety when taking Synjardy XR, tell your healthcare provider if you have ever had any of the following:

• Liver or kidney disease
• Bladder infection, trouble urinating
• Congestive heart failure, heart attack, stroke
• Genital infection
• Problems with your pancreas including surgery
• If you follow a low salt diet
• If you are older than 65 years of age

Avoid drinking alcohol often or in large quantities during treatment with Synjardy XR because it can increase adverse side effects.

Tell your healthcare provider if you are pregnant or plant to become pregnant while taking Synjardy XR. It is important to control your diabetes when pregnant, but this medication may cause harm if taken during the second or third trimesters of pregnancy.

Do not breastfeed while taking Synjardy XR.

Synjardy may stimulate ovulation in women who have not yet reached menopause which may increase your risk of having an unintended pregnancy. Use effective birth control and speak with your healthcare provider to learn more about your risk.

Some drugs may interact with Synjardy XR and cause adverse reactions. Tell your healthcare provider about all the medications that you take, especially any of the following:

• Topiramate and other carbonic anhydrase inhibitors (zonisamide, acetazolamide, and others)
• Ranolazine, vandetanib, dolutegravir, and cimetidine
• Diuretic medications
• Insulin or insulin secretagogues
• Thiazide medications
• Corticosteroids, phenothiazines, and thyroid medicines
• Estrogens, oral contraceptives
• Heart medications
• Lithium

Synjardy XR is not an approved treatment for anyone under the age of 18.

Form and Strength

This type 2 diabetes medication is available in the form of extended-release tablets.

Synjardy extended-release tablet strengths:

• 12.5mg empagliflozin / 500mg metformin
• 12.5/1000mg
• 25/1000mg

The 25/1000mg Synjardy XR tablets are available in quantities of 90 while the 12.5/500mg and 12.5/1000mg tablets are both available in quantities of 180.

FAQ

What are the instructions for Synjardy XR?

You should take your daily dose of Synjardy XR in the morning with food to help avoid gastrointestinal effects. Thanks to the medication’s extended-release form, you only need to take a single daily dose. During treatment, make sure that you avoid drinking large amounts of alcohol or in regular intervals to avoid an increase in adverse reactions.

Does Synjardy XR cause frequent urination?

A common side effect of Synjardy XR is urinating more frequently. This medication helps lower your blood sugar levels by increasing the amount of glucose that is passed in your urine. Make sure that you stay hydrated during treatment because this can reduce fluid levels in your body. Follow instructions offered by your healthcare provider for the best results.

Resources:

1. https://www.drugs.com/mtm/synjardy-xr.html
2. https://www.synjardy.com/taking-synjardy
3. https://content.boehringer-ingelheim.com/DAM/24ba79af-5d54-43cf-8f35-af1e012105ce/synjardy%20xr-us-pi.pdf
4. https://content.boehringer-ingelheim.com/DAM/74ab4c2f-ee56-4067-bf4a-af1e01211297/synjardy%20xr-us-mg.pdf