Safely Buy Afinitor ( Everolimus ) from Canada Prescriptions Plus.

Indications

Afinitor (chemical name: everolimus) is a prescription medication that belongs to a group of drugs called mTOR inhibitors.

Everolimus is used to treat several types of cancer, including advanced hormone receptor-positive, HER2-negative breast cancer, neuroendocrine tumours of the pancreas, and renal cell carcinoma.

Afinitor works by blocking a protein called mTOR, which is involved in the growth and division of cells. By blocking mTOR, Afinitor slows or stops cancer cells from growing and dividing, thereby helping to reduce the size of the tumour.

Use and Dosage

Take Afinitor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Take Afinitor at the same time each day. You may take the medicine with or without food but take it the same way each time.

Do not take a regular tablet together with a dispersible tablet. Use only one form of this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Afinitor can increase your risk of bleeding or infection by changing the way your immune system works. You will need frequent medical tests.

If you have ever had hepatitis B, using Afinitor can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.

Surgical incisions or other wounds may take longer to heal while you are taking Afinitor. You may need to stop taking this medicine for 1 week before and 2 weeks after surgery. Follow your doctor’s instructions.

Store at room temperature in the original container, away from moisture, heat, and light. Keep unused dispersible tablets in the foil blister pack.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to Afinitor: hives; chest pain, difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have some of these symptoms if you also take an “ACE inhibitor” heart or blood pressure medication.

Call your doctor at once if you have:

• Blisters or ulcers in your mouth, red or swollen gums, trouble swallowing
• Lung problems – new or worsening cough, chest pain, wheezing, feeling short of breath
• Signs of infection – fever, chills, tiredness, joint pain, skin rash
• Kidney problems – little or no urination; swelling in your feet or ankles
• Liver problems – nausea, loss of appetite, stomach pain (upper right side), dark urine, clay-coloured stools, jaundice (yellowing of the skin or eyes)
• Low blood cell counts – flu-like symptoms, skin sores, easy bruising, unusual bleeding, pale skin, cold hands, and feet, feeling light-headed
• Any wound that will not heal
• A surgical incision that is red, warm, swollen, painful, bleeding, or oozing pus

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects include:

• Fever, cough, infections, feeling weak or tired
• Mouth sores
• Nausea, loss of appetite
• Swelling anywhere in your body
• Rash
• Missed menstrual periods
• Headache
• High blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor

This is not a complete list of side effects and others may occur.

Cautions

Afinitor can cause serious and sometimes fatal side effects. Call your doctor right away if you have: signs of infection–fever, chills, skin rash, joint pain, tiredness; lung problems–cough, chest pain, wheezing, shortness of breath; kidney problems–swelling, little or no urination; or liver problems–loss of appetite, dark urine, yellowing of your skin or eyes, or upper stomach pain.

If you have ever had hepatitis B, Afinitor can cause this condition to come back or get worse.

You may be more likely to have an allergic reaction if you take an “ACE inhibitor” heart or blood pressure medication while you are taking Afinitor. Tell your doctor about all your current medicines and any you start or stop using.

Before taking this medicine, tell your doctor if you have a breathing disorder such as asthma or COPD, liver disease (or a history of hepatitis B), an active infection, diabetes or high blood sugar, or high cholesterol.

Do not use Everolimus if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medicine and for at least 8 weeks after your treatment ends.

Form and Strengths

Afinitor is available in the following form and strengths:

Afinitor Tablet:

• 2.5 mg
• 5 mg
• 10 mg

FAQ

What happens if I miss a dose?

Use the medicine as soon as you can but skip the missed dose if you are more than 6 hours late for the dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention.

What to avoid?

Do not receive a “live” vaccine while using Afinitor, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Grapefruit may interact with everolimus and lead to unwanted side effects. Avoid the use of grapefruit products.

Resources:

1. https://www.drugs.com/afinitor.html#warnings
2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
3. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2150f73a-179b-4afc-b8ce-67c85cc72f04