Safely Buy Amitiza ( Lubiprostone ) from Canada Prescriptions Plus.

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Prescription Required
Formulation : Capsule
Drug Name Dosage Quantity Price Buy Now
Amitiza 8mcg 60 $503.20 Add To Cart
Amitiza 24mcg 60 $391.20 Add To Cart
Dosage: 8mcg
Quantity: 60
Price: $503.20
Dosage: 24mcg
Quantity: 60
Price: $391.20

( Affordable Generic Alternatives )


Prescription Required
Formulation : Soft Gelatin Capsule
Drug Name Dosage Quantity Price Buy Now
Lubiprostone 24mcg 60 $60.50 Add To Cart
Lubiprostone 24mcg 180 $148.50 Add To Cart
Dosage: 24mcg
Quantity: 60
Price: $60.50
Dosage: 24mcg
Quantity: 180
Price: $148.50


Amitiza is a laxative medication used for the long-term treatment of chronic constipation, constipation caused by opioid medication, or constipation from irritable bowel syndrome (IBS).

Lubiprostone is a bicyclic fatty acid metabolite that helps encourage bowel movements by increasing your body’s secretion of gastrointestinal fluid. The drug does this by increasing intraluminal chloride ion secretion in your intestinal tract which augments water and sodium levels to improve your body’s ability to pass stool while decreasing transit time.

This medication is easily absorbed and acts locally in the intestinal tract. Amitiza is a well-tolerated treatment for chronic constipation with a rare occasion of adverse effects.

Uses and Dosage

The dose prescribed will vary depending on the individual and severity of the constipation being treated. Always follow your doctor’s directions and read packaging labels carefully.

  • Swallow capsule whole
  • Take with food and water
  • Most adults take 24mcg twice daily
  • For those with IBS, most take 8mcg twice daily
  • Do not take Amitiza if you have severe diarrhea
  • Store at room temperature away from light

Side Effects

Amitiza may cause some side effects to develop while it increases the fluid in your gastrointestinal tract. Speak with your doctor for more information regarding any symptoms you may encounter when taking lubiprostone.

Common Amitiza side effects:

  • Nausea, stomach pain
  • Diarrhea, gas, bloating
  • headache

Serious Side Effects

Some more serious side effects may occur when taking Amitiza. Stop using this medicine and contact your doctor if you notice any of the following symptoms:

  • Severe or ongoing nausea or diarrhea
  • Trouble breathing
  • Light-headed, feeling faint

This medication may cause your blood pressure to drop shortly after taking a dose, especially if you have been vomiting or have diarrhea. Contact your doctor if you feel light-headed each time you take a dose or if you develop severe diarrhea.

Allergic Reactions

Do not use Amitiza if you are allergic to lubiprostone. If you develop any signs of an allergic reaction, stop taking this medication and call your doctor.

Amitiza allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


Do not take Amitiza if your digestive tract is blocked or if you have severe diarrhea.

Lubiprostone may cause a decrease in blood pressure for a short period of time after taking each dose. If you feel faint or light-headed after each dose, stop using this medication and contact your doctor.

Amitiza may cause you to develop a tightness in your chest or shortness of breath within an hour of each dose.

This side effect should improve within 3 hours, but it may occur with your next dose. Consult with your doctor if this becomes bothersome.

To ensure the safety of taking this medication, tell your doctor if you have ever had liver disease.

Tell your doctor about all the medications you take because some may interact with lubiprostone to cause unwanted effects, these include over the counter medicines, vitamins, and herbal products. Ensure your doctor knows if you are using an opioid pain medicine.

Lubiprostone may cause nursing babies to develop diarrhea if taken by a breastfeeding mother. Contact your doctor if this happens.

Contact your doctor immediately if you develop severe or ongoing nausea or diarrhea.

Amitiza is not an approved constipation treatment for anyone under the age of 18.

Form and Strength

This laxative medication is available in capsule and soft gelatin capsule forms.

Amitiza capsule strengths:

  • 8mcg
  • 24mcg

Both strengths are available in quantities of 60.

Soft gelatin capsule strengths:

  • 24mcg

The 24mcg soft gelatin capsules are available in quantities of 60 or 180.


How long does it take for Amitiza to work?

Your body needs some time to absorb lubiprostone into your system and for it to take effect in your gastrointestinal system, but most have a bowel movement within 24 hours after taking the first dose. The first week of treatment should also see an increase in bowel motions.

How does Amitiza work?

Amitiza uses lubiprostone, a prostaglandin-derived bicyclic fatty acid, to increase water and sodium in your gastrointestinal tract. This action causes the muscles in your intestinal tract to relax which combines with increased fluid to improve stool transit time.



Additional information

Brand Name:


Scientific Name:


Other Names:

Amitiza, Lubowel


8mcg, 24mcg

Quantities Available:

60, 180


Capsule, Soft Gelatin Capsule