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Azilect is a type of medication prescribed to manage the symptoms of Parkinson’s disease.

Azilect is administered orally, in tablet form, and contains rasagiline mesylate as its active ingredient.

This substance is classified as a monoamine oxidase inhibitor (MAOI) and is responsible for increasing dopamine levels in the brain, which is important for controlling physical movements.

Azilect can be used either alone or in combination with other drugs, depending on the individual case.

Use and Dosage

Take this medication by mouth with or without food as directed by your doctor, usually once daily.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Do not increase your dose or take it more often than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

A very serious high blood pressure reaction may rarely occur if you eat a large amount of tyramine while taking rasagiline and for 2 weeks after you stop it. Avoid foods that are high in tyramine, like aged cheeses (such as Stilton cheese). Consult your doctor or dietician about which foods you should avoid and if you do not feel well after eating or drinking certain foods while taking this medication. See also the Side Effects section.

Tell your doctor if this medication stops working well or if your condition gets worse.

Side Effects

Common side effects include:

  • Nausea
  • Dizziness
  • Headache
  • Drowsiness
  • Heartburn
  • Dry mouth
  • Stomach upset
  • Loss of appetite
  • Weight loss
  • Joint pain
  • Constipation
  • Diarrhea

In most cases, the side effects brought about by this prescription medication are mild and will resolve even without medical intervention. However, if the adverse reactions persist or get worse, you must consult your doctor or any healthcare professional immediately.

Severe side effects include:

  • Fainting
  • Loss of balance
  • Worsening muscle stiffness
  • Swollen ankles
  • Easy bruising and bleeding
  • Unusual strong urges
  • Mental or mood changes
  • Hypertensive crisis (severe headache, irregular heartbeat, chest pain, neck stiffness, severe vomiting, widened pupils, increased sensitivity to light)
  • Symptoms of serotonin syndrome (fast heartbeat, hallucinations, agitation, loss of coordination, severe dizziness, unexplained fever)

This is not a complete list of Azilect’s side effects.


Before starting to use this prescription drug, you must disclose your complete medical history with your physician, especially any history of stroke, heart disease, high blood pressure or hypertension, migraine, liver disease, hyperthyroidism, diabetes, pheochromocytoma, sleep disorder, or mental disorder. Some conditions may impact how you will respond to treatment. Moreover, you should talk about all the prescription drugs and nonprescription drugs you are taking because of possible Azilect drug interactions.

While on this therapy, keep an eye out for any allergic reactions. Do not take this oral MAOI if you have a known allergy to rasagiline or any inactive ingredients it may contain. Signs of hypersensitivity are breathing difficulty, severe dizziness, swelling of the face and neck, hives, and skin rashes. If this occurs, you must immediately discontinue medication and seek emergency medical attention.

Consuming foods that are high in tyramine could increase the risk of hypertensive crisis. To avoid such conditions, do not eat food that has high tyramine content, such as aged cheeses and cured meats.

Stop drinking any alcoholic beverages while on this treatment. Alcohol could interact with rasagiline and worsen adverse effects, such as dizziness, drowsiness, and falling asleep suddenly. You must also practice extreme safety precautions when doing activities that require alertness, like driving.

It is still unknown whether this prescription drug can pose harm to unborn babies and breastfed children. Moms who are pregnant or breastfeeding must use this drug only if needed.

Form and Strengths

Azilect is available in the following form and strengths:

  • Azilect Tablet:
    • 0.5 mg
    • 1 mg
  • Rasagiline Tablet:
    • 0.5 mg
    • 1 mg


Is rasagiline effective for Parkinson’s disease?

Clinical trials on Azilect & Parkinson’s disease have proven this to be a safe and effective medication to manage the disease.

Does Azilect make you feel sleepy?

This medication causes drowsiness and could make you fall asleep suddenly.

What food should I avoid when taking Azilect?

Azilect foods to avoid:

  • Smoked or processed meats
  • Cured meats
  • Aged cheeses
  • Fermented food
  • Soybean products
  • Broad beans
  • Dried fruits



Additional information

Brand Name:


Scientific Name:


Other Names:

Azilect, Rasalect


0.5mg, 1mg

Quantities Available:

30, 90, 100