Safely Buy Bonefos ( Clodronate Disodium ) from Canada Prescriptions Plus.

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Formulation : Capsule
Drug Name Dosage Quantity Price Buy Now
Bonefos 400mg 120 $283.25 Add To Cart
Dosage: 400mg
Quantity: 120
Price: $283.25


Bonefos (clodronate) is a medication that belongs to a class of drugs called bisphosphonates. It is used for various purposes, including reducing the occurrence of bone metastases, treating hypercalcemia (high blood calcium), and managing bone destruction due to breast cancer and bone marrow cancer.

Please note that Bonefos is not FDA-approved in the United States, but it is used in several other countries, including Canada, Australia, the United Kingdom, and Italy).

Use and Dosage

The usual recommended dose of clodronate is 1,600 mg to 2,400 mg daily given as a single daily dose or as 2 divided doses. The maximum recommended daily dose is 3,200 mg. Your doctor may adjust your dose depending on how well this medication is working for you.

Clodronate capsules should be swallowed whole (not chewed) on an empty stomach while sitting in an upright position. Take this medication with a glass of plain water, at least 2 hours before or after food. Do not take this medication with milk. Do not lie down for at least 30 minutes after taking the medication to prevent any irritation to your esophagus (the tube connecting the mouth and stomach).

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of reach of children and pets.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Side Effects

Bonefos (clodronate disodium) may cause certain side effects. Here are some common side effects associated with Bonefos:

  • Gastrointestinal Effects: Bonefos may cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal pain.
  • Hypocalcemia: Bonefos can lower calcium levels in the blood, leading to hypocalcemia. Symptoms of hypocalcemia may include muscle cramps, numbness or tingling in the fingers or around the mouth, and seizures. Monitor calcium levels during treatment with Bonefos.
  • Renal Effects: Bonefos can affect kidney function. Monitor kidney function regularly during treatment.
  • Flu-like Symptoms: Some individuals may experience flu-like symptoms such as fever, fatigue, and body aches while taking Bonefos.
  • Allergic Reactions: In rare cases, allergic reactions to Bonefos may occur. Symptoms of an allergic reaction may include rash, itching, swelling, dizziness, and difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.


  • Clodronate may potentially cause kidney problems. If you have reduced kidney function or a history of kidney disease, discuss this with your healthcare professional before starting treatment with Bonefos.
  • Bonefos can lower calcium levels in the blood, leading to hypocalcemia. This is why monitor calcium levels during treatment with Bonefos. If you experience symptoms such as muscle cramps, numbness or tingling, or seizures, seek medical attention.
  • Bonefos may cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal pain. If these symptoms become severe or persistent, it is advisable to consult with a healthcare professional.
  • Although rare, allergic reactions to Bonefos may occur. If you experience symptoms such as rash, itching, swelling, dizziness, or difficulty breathing, seek immediate medical attention.
  • The use of Bonefos during pregnancy and breastfeeding should be discussed with a healthcare professional. Weigh the potential benefits against the potential risks.
  • The use of Bonefos and the dosage may vary depending on the specific condition being treated and the individual patient. Follow the prescribed dosage and consult with a healthcare professional for personalized advice and instructions.

Forms and Strengths

Bonefos is available in the following forms and strengths:

  • Bonefos Capsule:
    • 400 mg
    • 800 mg




How does Bonefos work?

Bonefos works by inhibiting the breakdown of bone tissue. It helps to reduce bone pain and prevent complications associated with bone metastases in cancer patients.

What conditions are Bonefos used to treat?

Bonefos is primarily used to manage bone pain caused by cancer that has spread to the bones. Not intended for the treatment of osteoporosis or other non-cancer-related bone conditions.

Can Bonefos be used for same-day delivery?

Yes, Bonefos can be delivered on the same day. However, consult with a healthcare professional or a pharmacy to confirm the availability and delivery options in your specific location.

Additional information

Brand Name:


Scientific Name:

Clodronate Disodium

Other Names:




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