Clenpiq

Indications

Clenpiq is an oral solution used for colon cleansing as a preparation for colonoscopy in adults and pediatric patients ages 9 years and older. It contains sodium picosulfate, magnesium oxide, and anhydrous citric acid, which form magnesium citrate, a stimulant laxative that helps to create bowel movements and empty the colon.

Clenpiq belongs to a class of drugs called Bowel Preps.

Use and Dosage

The Split-Dose regimen is the preferred dosing method. The recommended dosage in adults and pediatric patients 9 years of age and older is shown below. Instruct patients to take two separate doses in conjunction with fluids, as follows:

• Dose 1 – On the Day before Colonoscopy
  • Instruct patients to consume only clear liquids (no solid food or dairy) on the day before the colonoscopy up to 2 hours before the time of the colonoscopy.
  • Take the first dose (1 bottle) of Clenpiq during the evening before the colonoscopy (e.g., 5:00 to 9:00 PM).
  • Follow Clenpiq by drinking five 8-ounce cups (cup provided) of clear liquids (40 ounces total) within 5 hours and before bed.
  • If severe bloating, distention, or abdominal pain occurs, following the first dose, delay the second dose until the symptoms resolve.
• Dose 2 – Next Morning On The Day Of Colonoscopy (Start Approximately 5 Hours Before Colonoscopy)
  • Continue to consume only clear liquids (no solid food or dairy).
  • Take the second dose (the second bottle) of Clenpiq.
  • Following the Clenpiq dose, drink at least three 8-ounce cups (cup provided) of clear liquids (24 ounces) at least 2 hours before the colonoscopy.

Side Effects

Common side effects include:

• Frequent and very watery bowel movements
• Nausea
• Headache
• Bloating
• Stomach cramps
• Vomiting

In most cases, the side effects brought about by this medication are mild and temporary. If the adverse reactions get worse or do not get better even after a few days, you must call your doctor or any healthcare professional.

Severe side effects include:

• Confusion
• Severe dizziness
• Fainting
• Seizure
• Irregular heartbeat
• Severe and persistent abdominal pain
• Bloody stool
• Rectal bleeding
• Signs of kidney problems (changes in urine output)

This is not a complete list of the side effects of Clenpiq.

Cautions

Before you start taking this oral solution, you must disclose your entire medical history to your physician, especially salt or mineral imbalance, heart problems, seizure, kidney problems, gastrointestinal disorders, or trouble swallowing. Some diseases or disorders may significantly impact how you will respond to this medication.

Avoid taking this prescription drug if you have a known allergy to sodium picosulfate, magnesium oxide, anhydrous citric acid, or any inactive ingredients that this medication may contain. Signs of severe allergic reactions are breathing trouble, skin rashes, swelling of the face and neck, hives, and severe dizziness. If this occurs, alert your local medical emergency line.

Pregnant or breastfeeding moms must use this medication only if highly needed. This is because there are still no definitive clinical trials to tell whether this medication could cause harm to unborn babies and breastfed infants.

Form and Strengths

Clenpiq is available in the following form and strengths:

Clenpiq Tablet:

• 10mg/3.5g/5g

FAQ

What does Clenpiq taste like?

This bowel preparation tastes like a very sweet juice.

How long does it take for Clenpiq to work?

You may start to have watery stool 2 to 4 hours after taking the bottle of this medication.

What is a good Clenpiq alternative?

There is no equivalent version for this medication.

Resources:

1. https://www.rxlist.com/clenpiq-drug.htm#indications
2. https://www.drugs.com/dosage/clenpiq.html
3. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ea24a07b-34ca-4da4-ba69-73bbf44de20d