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Docusate Sodium - non Rx

Prescription Not Required
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Colace is a medication prescribed to help relieve constipation by softening stool. This medication helps reduce pain and rectal damage that hard stools or straining during bowel movements can produce.

Docusate Sodium increases the amount of water in stool and reduces tension in the colon to make defecating less effort. Thanks to this, Colace is helpful for those who have difficulty passing stools because of hemorrhoids or other conditions.

Uses and Dosage

Use Colace as directed on the label and by your doctor. Do not use a larger dose for longer than recommended.

  • Take with a full glass of water
  • Stay hydrated while taking Colace
  • Adults should take no more than 300mg per day in divided doses
  • Children 2 to 12 years should take no more than 150mg divided each day
  • Colace usually produces bowel movements within 12 to 72 hours
  • Do not take this medicine for longer than one week
  • Keep packaging closed tightly
  • Store at room temperature away from light, heat, and moisture
  • Do not let liquid medicine freeze

Side Effects

This medication may not provide any side effects for you, but because it affects the water in your body and stool, it may cause some. Consult with your doctor for more information concerning any you may encounter.

Serious Side Effects

Stop taking Colace and call your doctor if you notice any of the following side effects:

  • Rectal bleeding
  • No bowel movement occurs after taking the laxative
  • You need to use a stool softener more than once a week
  • A rash appears

Allergic Reactions

Do not take Colace if you are allergic to Docusate Sodium. Stop using this medication and seek immediate medical attention if you notice any signs of an allergic reaction.

Colace allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


Do not use this medication if you are taking mineral oil, unless directed by a doctor.

Before taking Colace, consult with your doctor if you have any of the following:

  • Stomach pain
  • Nausea
  • Vomiting
  • Sudden change in bowel habits over the last two weeks

Ask a doctor before using if you are pregnant or breastfeeding.

Other medications including vitamins and herbal products may interact with Colace and cause unwanted side effects.

Consult with your doctor and let them know about any medications you are taking or plan to stop using.

Form and Strength

This medication is available in capsule and syrup forms.

Colace strengths:

  • Syrup

      10mg/mL in quantities of 30mL

      60mg/15mL in 250mL

      100mg in 100mL

  • Capsules

    • 100mg in quantities of 100


Do I need to take Colace with food?

No, Colace can be taken with or without food.

How long does Colace take to work?

Colace should produce a bowel movement within 12 to 72 hours after it has been taken. If you suffer from pain associated with constipation while sleeping, it is recommended to take it before you fall asleep for overnight relief.



Additional information

Brand Name:


Scientific Name:

Docusate Sodium – Generic Non Rx, Docusate Sodium – non Rx

Other Names:

Colace, Docusate Sodium


10mg/mL, 60mg/15mL, 100mg

Quantities Available:

30mL, 100, 250mL


Capsule, Drops, Syrup