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Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Comtan 200mg 90 $129.30 Add To Cart
Dosage: 200mg
Quantity: 90
Price: $129.30

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Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Entacapone 200mg 100 $66.15 Add To Cart
Dosage: 200mg
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Price: $66.15


Comtan is a brand-name medication containing the active ingredient entacapone, which is used to treat patients with Parkinson’s disease as an adjunct to the levodopa/carbidopa regimen.

Parkinson’s disease is a progressive brain disorder that causes shaking, slow movement, and muscle stiffness.

Entacapone works by blocking a certain natural substance (COMT enzyme) that breaks down levodopa, thus allowing the levodopa to last longer in the body and providing greater symptom control.

Use and Dosage

Take this medication by mouth with or without food, usually with each prescribed dose of levodopa/carbidopa (up to 8 times daily) or as directed by your doctor.

Dosage is based on your medical condition, liver function, and response to therapy.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not suddenly stop taking this medication unless instructed to do so by your doctor. Doing so may cause your Parkinson’s symptoms to become much worse.

Tell your doctor if your condition lasts or gets worse (such as if your Parkinson’s symptoms are not controlled).

Side Effects

It is common to experience: dizziness, drowsiness, nausea, vomiting, stomach pain, dry mouth, and involuntary muscle movements when taking this medication. Talk to your doctor about any of these side effects if they are severe or do not go away. Immediately seek medical help from your healthcare provider if you experience any of the following dangerous side effects:

Severe Side Effects include:

  • Hallucinations
  • Diarrhea
  • Decrease in blood pressure (increased sweating, falling, fainting, severe dizziness)
  • Chest pain
  • Swelling or blueness in the extremities
  • Somnolence (excessive sleepiness, drowsiness)
  • Muscle stiffness
  • Muscle twitching
  • Shaking
  • Confusion
  • Increases in heart rate or temperature
  • Hepatitis (loss of appetite, weakness, exhaustion, jaundice, darkened urine)
  • Skin rashes, blisters, or redness
  • Allergic reactions (Rashes, swelling of the face or throat, difficulty breathing)


Before taking entacapone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: alcoholism, liver problems, low blood pressure, mental/mood disorders (such as depression, schizophrenia), and sleep disorders.

This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). See also the Side Effects section.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially drowsiness and confusion.

During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Form and Strengths

  • Comtan Tablet:
    • 200 mg
  • Entacapone Tablet:
    • 200 mg


Who Should Not Use Comtan?

Tell your doctor if you have:

  • Low blood pressure
  • Liver, heart, blood, or lung diseases
  • Mental illnesses or psychosis
  • A hypersensitivity to entacapone or similar medications.
  • Developed rhabdomyolysis
  • Inflammatory Bowel Disease

Is Comtan available over the counter?

No, Comtan is not available over the counter. It is available by prescription only.



Additional information

Brand Name:


Scientific Name:


Other Names:

Comtess, Entacom



Quantities Available:

90, 100