Safely Buy Cuprimine ( Penicillamine ) from Canada Prescriptions Plus.

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Prescription Required
Formulation : Capsule
Drug Name Dosage Quantity Price Buy Now
Penicillamine 125mg 56 $105.20 Add To Cart
Penicillamine 125mg 112 $195.60 Add To Cart
Penicillamine 250mg 100 $58.20 Add To Cart
Dosage: 125mg
Quantity: 56
Price: $105.20
Dosage: 125mg
Quantity: 112
Price: $195.60
Dosage: 250mg
Quantity: 100
Price: $58.20


Cuprimine, also known as penicillamine, is a medication used to treat Wilson’s disease, cystinuria, and severe, active rheumatoid arthritis that has not responded to other treatments.

Cuprimine is a chelating agent that binds to excess copper and removes it from the bloodstream.

Use and Dosage

Take this medication by mouth on an empty stomach (1 hour before or 2 hours after meals) as directed by your doctor. Take this medication at least 1 hour apart from other drugs (especially antacids), milk, or food.

Dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Your doctor may also direct you to take vitamin B6 (pyridoxine) and iron. Follow your doctor’s instructions carefully. If you need to take iron or other products that contain minerals (such as zinc), take it at least 2 hours before or after taking penicillamine. Consult your doctor before taking any products containing minerals since they may block the absorption of penicillamine.

Side Effects

Serious side effects include:

  • Joint pain
  • Muscle weakness
  • Drooping eyelids
  • Double vision
  • Trouble chewing
  • Cough
  • Fever
  • Difficulty breathing
  • Edema symptoms (swelling) of the hands or feet
  • Mouth ulcers
  • Swollen gums
  • Back pain
  • Difficulty urinating or blood in the urine
  • Fatigue, chills, and fever
  • Skin sores
  • Unusual bleeding

Using this prescription drug can cause blood cell deficiency. Signs of low blood cells include fever, fatigue, cold or clammy skin, paleness, light-headedness, shortness of breath, and unusual bleeding.


Before taking penicillamine, tell your doctor or pharmacist if you are allergic to it; or to penicillins; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a previous severe reaction to penicillamine (such as aplastic anemia, agranulocytosis), kidney disease, and blood/bone marrow disorders (such as thrombocytopenia).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using penicillamine. Penicillamine may harm an unborn baby. However, it may sometimes be used during pregnancy in certain situations (such as treating Wilson’s disease). If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.

It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breastfeeding while using this drug is not recommended. Consult your doctor before breastfeeding.

Form and Strengths

Cuprimine is available in the following form and strengths:

  • Penicillamine Capsule:
    • 125 mg
    • 250 mg


What happens if I miss a dose?

Take the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while taking Cuprimine?

Avoid taking other medicines at the same time as you take Cuprimine. If you take an iron supplement, take it at least 2 hours before or 2 hours after you take this medicine. Iron can make it harder for your body to absorb this medicine. Avoid taking mineral supplements unless your doctor tells you to.



Additional information

Brand Name:


Scientific Name:


Other Names:

Cilamin, Penicillamine


125mg, 250mg

Quantities Available:

56, 100, 112


Capsule, Tablet