Safely Buy Duaklir Pressair ( Aclidinium Bromide/Formoterol Fumarate ) from Canada Prescriptions Plus.

Indications

Duaklir Pressair is a prescription medication used to prevent airflow obstruction and reduce flare-ups in adults with Chronic Obstructive Pulmonary Disease (COPD).

Duaklir Pressair is a combination medication that contains two active ingredients – aclidinium bromide, which is an anticholinergic, and formoterol fumarate, which is a long-acting beta2-adrenergic.

Duaklir Pressair comes in inhaler form and works by relaxing the muscles in the airways to help the patient breathe more easily and is not indicated for the relief of acute bronchospasm or the treatment of asthma.

Use and Dosage

Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. Follow the illustrated directions for the proper use of this medication. If you have any questions, ask your doctor or pharmacist.

Inhale this medication by mouth as directed by your doctor, usually twice daily (once in the morning and once in the evening). You may or may not taste the drug when you inhale it. Do not exhale into the device. Avoid getting any of this medication in your eyes.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

Do not increase your dose, use this medication more often, or stop using it without first consulting your doctor. Your condition will not improve any faster, and your risk of side effects will increase.

If you are using other inhalers at the same time, wait at least 1 minute between the uses of each medication.

If you have been using a quick-relief inhaler (such as albuterol, also called salbutamol in some countries) on a regular daily schedule (such as 4 times daily), you must stop this schedule and only use the quick-relief inhaler as needed for sudden shortness of breath. Consult your doctor for details.

Learn which of your inhalers you should use every day and which you should use if your breathing suddenly worsens (quick-relief drugs). Ask your doctor ahead of time what you should do if you have a new or worsening cough or shortness of breath, wheezing, increased sputum, waking up at night with trouble breathing, if you use your quick-relief inhaler more often, or if your quick-relief inhaler does not seem to be working well. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away.

Tell your doctor if your condition does not get better or if it gets worse.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Serious side effects include:

• Wheezing, choking, or other breathing problems after using aclidinium and formoterol
• Worsening breathing problems
• Tremors, nervousness, chest pain, or fast or pounding heartbeats
• Severe headache or pounding in your neck or ears
• Painful or difficult urination, or urinating more often
• Blurred vision, tunnel vision, eye pain or redness, or seeing halos around lights
• High blood sugar–increased thirst or urination, hunger, dry mouth, fruity breath odour; or low potassium level–leg cramps, constipation, irregular heartbeats, fluttering in your chest, numbness or tingling, or muscle weakness or limp feeling

Common side effects of aclidinium and formoterol may include:

• Headache
• Back pain
• Cold symptoms such as stuffy nose, sneezing, or sore throat

This is not a complete list of side effects and others may occur.

Cautions

Before using aclidinium/formoterol, tell your doctor or pharmacist if you are allergic to either drug or if you have any other allergies. This product may contain inactive ingredients (such as milk proteins), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as chest pain, irregular heartbeat), high blood pressure, seizures, overactive thyroid, diabetes, personal or family history of glaucoma (angle-closure type), difficulty urinating (such as due to an enlarged prostate), a certain tumour of the adrenal gland (pheochromocytoma).

Aclidinium/formoterol may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, and fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using aclidinium/formoterol, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/”water pills”) or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using aclidinium/formoterol safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).

During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

Form and Strengths

Duaklir Pressair is available in the following form and strengths:

• Duaklir Pressair Inhalation Powder:
  • 400/12 mg

FAQ

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. Do not use more than 1 inhalation 2 times in 24 hours.

What happens if I overdose?

Seek emergency medical attention.

Overdose symptoms may include blurred vision, dry mouth, nausea, muscle spasms, tremors, headache, and fast or pounding heartbeats.

What should I avoid while using aclidinium and formoterol?

Do not use a second inhaled bronchodilator that contains formoterol, arformoterol, indacaterol, olodaterol, salmeterol, or formoterol.

Resources:

1. https://www.webmd.com/drugs/2/drug-178032/duaklir-pressair-inhalation/details
2. https://www.drugs.com/mtm/aclidinium-and-formoterol.html#side-effects
3. https://pubmed.ncbi.nlm.nih.gov/31599867/
4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210595lbl.pdf