Safely Buy Estraderm Patch ( Estradiol ) from Canada Prescriptions Plus.

( Top Brand Option )

Estraderm Patch

Prescription Required
Formulation : Trandsdermal Patch
Drug Name Dosage Quantity Price Buy Now
Estraderm Patch 25mcg 8 $61.50 Add To Cart
Estraderm Patch 25mcg 16 $81.95 Add To Cart
Estraderm Patch 25mcg 24 $75.10 Add To Cart
Estraderm Patch 50mcg 24 $81.30 Add To Cart
Estraderm Patch
Dosage: 25mcg
Quantity: 8
Price: $61.50
Estraderm Patch
Dosage: 25mcg
Quantity: 16
Price: $81.95
Estraderm Patch
Dosage: 25mcg
Quantity: 24
Price: $75.10
Estraderm Patch
Dosage: 50mcg
Quantity: 24
Price: $81.30

( Affordable Generic Alternatives )


Prescription Required
Formulation : Patch
Drug Name Dosage Quantity Price Buy Now
Estradiol 50mcg 8 $46.10 Add To Cart
Estradiol 50mcg 16 $72.10 Add To Cart
Estradiol 75mcg 8 $49.10 Add To Cart
Estradiol 75mcg 16 $77.10 Add To Cart
Estradiol 100mcg 8 $50.20 Add To Cart
Estradiol 100mcg 16 $84.10 Add To Cart
Estradiol 100mcg 24 $118.10 Add To Cart
Dosage: 50mcg
Quantity: 8
Price: $46.10
Dosage: 50mcg
Quantity: 16
Price: $72.10
Dosage: 75mcg
Quantity: 8
Price: $49.10
Dosage: 75mcg
Quantity: 16
Price: $77.10
Dosage: 100mcg
Quantity: 8
Price: $50.20
Dosage: 100mcg
Quantity: 16
Price: $84.10
Dosage: 100mcg
Quantity: 24
Price: $118.10


This medication is a hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness).

These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected.

Use and Dosage

Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Peel off the backing from the patch and apply the patch to a clean, dry area of the body as directed. This patch should only be applied to certain areas of the body. Different brands of patches are applied to different areas of the body. If you have any questions about where to apply the patch, ask your doctor or pharmacist. Press the patch firmly in place for about 10 seconds to make sure it stays on. Do not apply the patch on the breast or oily, broken, or irritated skin. Avoid applying the patch to areas of the skin where it might be easily rubbed off (such as the waistline). Use this medication as directed by your doctor. The patch is usually replaced twice a week (every 3 to 4 days). Follow the dosing schedule carefully.

The dosage is based on your medical condition and response to treatment.

When replacing your patch, make sure to apply the new patch to a different area. Wait at least 1 week before applying a patch to the same area. Fold the old patch in half with the sticky side together and throw it away in the trash away from children and pets. Do not flush the patch down the toilet.

If a patch falls off, reapply it to a different area. If the patch does not stick completely, then apply a new patch and wear it for the rest of the scheduled period. Do not wear 2 patches at the same time.

Use this medication regularly to get the most benefit from it. To help you remember, change the patch on the same days each week. It may help to mark your calendar as a reminder.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Ransdermal estradiol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • Headache
  • Breast pain or tenderness
  • Nausea
  • Vomiting
  • Constipation
  • Gas
  • Heartburn
  • Weight gain or loss
  • Hair loss
  • Redness or irritation of the skin that was covered by the estradiol patch
  • Swelling, redness, burning, irritation or itching of the vagina
  • Vaginal discharge
  • Painful menstrual periods
  • Anxiety
  • Depression
  • Changes in mood
  • Change in sexual desire
  • Back, neck, or muscle pain
  • Runny nose or congestion
  • Darkening of the skin on the face (may not go away even after you stop using transdermal estradiol)
  • Unwanted hair growth
  • Difficulty wearing contact lenses
  • Joint pain

Some side effects can be serious

If you experience any of these symptoms, call your doctor immediately:

  • Yellowing of the skin or eyes
  • Loss of appetite
  • Fever
  • Stomach tenderness, pain, or swelling
  • Itching
  • Hives
  • Rash, blisters on the skin, or other skin changes
  • Swelling, of the eyes, face, lips, tongue, throat, hands, feet, ankles, or lower legs
  • Hoarseness
  • Difficulty breathing or swallowing

Transdermal estradiol may increase your risk of developing cancer of the ovaries and gallbladder disease that may need to be treated with surgery. Talk to your doctor about the risks of using transdermal estradiol.


  • Before using estradiol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, a certain blood disorder (porphyria), mental/mood disorders (such as dementia, depression).
  • Do not smoke or use tobacco. Estrogens combined with smoking further increases your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35.
  • Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are taking an estrogen product. You may need to stop this medication for a time or take special precautions.
  • If you are going to have an MRI test, tell testing personnel that you are using this patch. Some patches may contain metals that can cause serious burns during an MRI. Ask your doctor whether you will need to remove your patch before the test and apply a new patch afterward, and how to do so properly.
  • This medication may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.
  • If you are nearsighted or wear contact lenses, you may develop vision problems or trouble wearing your contact lenses. Contact your eye doctor if these problems occur.
  • Children may be more sensitive to the side effects of this drug. It may affect their growth/development. Discuss the possible effects of this medication with the doctor and monitor your child’s growth periodically.
  • This medication should not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away.
  • This medication passes into breast milk. It may reduce the quality and amount of breast milk produced. Consult your doctor before breast-feeding.

Forms and Strengths

Estraderm Patch is available in the following forms and strengths:

  • Estraderm Patch Trandsdermal Patch:
    • 25 mcg
    • 50 mcg
  • Estradiol Patch:
    • 50 mcg
    • 75 mcg
    • 100 mcg


How does Estraderm Patch work?

Estraderm Patch delivers estradiol through the skin into the bloodstream. Estradiol is a form of estrogen that helps replenish the declining levels of estrogen in menopausal women, thereby alleviating menopausal symptoms.

How should I apply the Estraderm Patch?

To apply the Estraderm Patch, follow these steps:

  • Clean and dry the area of the skin where you will apply the patch.
  • Remove the protective liner from the patch.
  • Press the sticky side of the patch firmly against your skin.
  • Ensure that the patch is firmly attached, especially around the edges.
  • Wear the patch continuously until it is time to replace it.

Where can I apply the Estraderm Patch?

The Estraderm Patch can be applied to various areas of the body, such as the lower abdomen, buttocks, or hips. Follow the specific instructions provided by your healthcare provider or the product packaging.

Can I swim or bathe while wearing the Estraderm Patch?

The Estraderm Patch is designed to be water-resistant, allowing you to engage in normal activities such as swimming or bathing. However, check the specific instructions provided by your healthcare provider or the product packaging.

Can I use the Estraderm Patch if I have a history of breast cancer?

Discuss your medical history, including any history of breast cancer, with your healthcare provider before using the Estraderm Patch. They can assess the potential risks and benefits based on your circumstances.



Additional information

Brand Name:

Estraderm Patch

Scientific Name:

Estradiol, Estradiol Hemihydrate

Other Names:

Estraderm MX, Estradiol Patch


25mcg, 50mcg, 75mcg, 100mcg

Quantities Available:

8, 16, 24


Patch, Trandsdermal Patch