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Frovatriptan Succinate

Prescription Required
Formulation : Tablet
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Frova is a medication used to treat migraines with or without aura in adults. It helps to relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light and sound).

Frova is not intended to prevent migraines. There is a medical device called the Frova Intubating Introducer, which is used to facilitate endotracheal intubation in adult patients where visualization of the glottis is inadequate.

Use and Dosage

Read the Patient Information Leaflet if available from your pharmacist before you start taking frovatriptan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, at the first sign of a migraine. It may be taken with or without food but may work faster when it is taken on an empty stomach. The dosage is based on your medical condition and response to treatment. If there is no improvement in your symptoms, do not take more doses of this medication before talking to your doctor.

If your symptoms are only partly relieved or if your headache comes back, the U.S. manufacturer recommends that you may take another dose after 2 hours, up to a maximum of 3 doses (7.5 milligrams) in 24 hours. The Canadian manufacturer recommends that you may take another dose after 4 hours, up to a maximum of 2 doses (5 milligrams) in 24 hours. Carefully follow your doctor’s directions for using this medication.

If you have a higher risk for heart problems (see Precautions), your doctor may perform a heart exam before you start taking frovatriptan. He/she may also direct you to take your first dose of this medication in the office/clinic to monitor for serious side effects (such as chest pain). Talk to your doctor for details.

If you are using drugs for migraine attacks on 10 or more days each month, the drugs may make your headaches worse (medication overuse headache). Do not use medications more often or for longer than directed. Tell your doctor if you need to use this medication more often, if the medication is not working as well, or if your headaches get worse.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Frova may cause serious side effects. Stop using Frova and call your doctor at once if you have:

  • Sudden and severe stomach pain and bloody diarrhea
  • Severe chest pain, shortness of breath, or irregular heartbeats
  • A seizure (convulsions)
  • Blood circulation problems in your legs or feet–cramps, tight or heavy feeling, numbness or tingling, muscle weakness, burning pain, cold feeling, color changes (pale or blue), or hip pain
  • Heart attack symptoms–chest pain or pressure, pain spreading to your jaw or shoulder, nausea, or sweating
  • High levels of serotonin in the body–agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, or fainting
  • Increased blood pressure–severe headache, blurred vision, pounding in your neck or ears, anxiety, or nosebleed
  • Signs of a stroke–sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, or problems with vision or balance

Common side effects of Frova may include:

  • Mild headache (not a migraine)
  • Feeling too warm or too cold
  • Dry mouth or upset stomach
  • Chest pain
  • Bone or joint pain
  • Numbness or tingling in your fingers or toes
  • Dizziness or tiredness
  • Flushing (warmth, redness, or tingly feeling)

This is not a complete list of side effects and others may occur.


Before taking frovatriptan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (for example, in your legs, arms/hands, or stomach), certain types of headaches (hemiplegic or basilar migraine), heart problems (such as chest pain, irregular heartbeat, and previous heart attack), liver disease, seizure, stroke or “mini-stroke” (transient ischemic attack).

Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions, including high blood pressure, high cholesterol, diabetes, family history of heart disease, overweight, smoker, postmenopausal (women), or age more than 40 years (men).

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you dizzier. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

The risk of heart disease and high blood pressure increases with age. Older adults may be more sensitive to the side effects of this drug, especially increased blood pressure and heart problems.

During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Form and Strengths

Frova is available in the following form and strengths:

  • Frova Tablet:
    • 2.5 mg
  • Frovatriptan Succinate Tablet:
    • 2.5 mg


What happens if I miss a dose?

Since Frova is used when needed, it does not have a daily dosing schedule. Call your doctor if your symptoms do not improve after using Frova.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while using Frova?

Do not take Frova within 24 hours before or after using another migraine headache medicine, including: sumatriptan, almotriptan, eletriptan, naratriptan, rizatriptan, zolmitriptan; orergot medicine such as dihydroergotamine, ergotamine, ergonovine, or methylergonovine.

Avoid driving or hazardous activity until you know how Frova will affect you. Your reactions could be impaired.



Additional information

Brand Name:


Scientific Name:

Frovatriptan Succinate

Other Names:

Frovatriptan, Migard, Migrex



Quantities Available:

6, 18, 24, 30, 48