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Prescription Required
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Dosage: 160mg
Quantity: 30
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Megestrol Acetate

Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Megestrol Acetate 40mg 100 $149.50 Add To Cart
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Megestrol Acetate
Dosage: 40mg
Quantity: 100
Price: $149.50
Megestrol Acetate
Dosage: 160mg
Quantity: 100
Price: $600.10


Megace is a steroid medication used to treat anorexia, cachexia, and unexplained weight loss in those with acquired immunodeficiency syndrome.

Megestrol acetate is a synthetic derivative of the female hormone progesterone that encourages weight gain. The specific mechanism of action of Megace is unknown but its effects may be in part thanks to its ability to increase body fat.

Uses and Dosage

The dose of Megace prescribed will vary depending on the individual and condition being treated. Always follow your doctor’s instructions and read packaging labels carefully when taking medication.

  • Swallow tablets whole
  • For breast cancer, most adults take 160mg daily divided into four doses
  • For endometrial carcinoma, most take 40 to 320mg daily in divided doses
  • For anorexia, cachexia, or weight loss, adults take 625mg daily
  • Most treatment should be continued for at least 2 months to see optimal results
  • Ask your doctor before stopping this medication to learn ways to avoid withdrawal
  • Store at room temperature away from moisture and heat

Side Effects

Megace may cause some side effects to develop while it stimulates your appetite. Speak with your doctor for more in-depth information regarding symptoms you may encounter when taking megestrol acetate.

Common Megace side effects:

  • Nausea, gas, diarrhea
  • Increased blood pressure
  • Impotence, sexual problems
  • Skin rash
  • weakness

Serious Side Effects

Some more serious adverse effects may occur when taking megestrol acetate. Stop using Megace and call your doctor if you develop any of the following symptoms:

  • Chest pain, sudden cough, wheezing, rapid breathing, coughing blood
  • Swelling, warmth, or redness in an arm or leg
  • Increased thirst, increased urination, dry mouth, fruity breath odor
  • Weight gain (especially in waist and upper back)
  • Muscle weakness, tiredness, feeling light-headed
  • Skin discolouration, thinning skin, increased body hair
  • Changes in mood, menstruation, or sex

Allergic Reactions

Do not use Megace if you are allergic to megestrol acetate. If you notice signs of an allergic reaction, stop using this medication and call your doctor.

Megace allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


Do not use Megace if you are pregnant; megestrol acetate may cause low birth weight and other complications when used during pregnancy. Use effective birth control during treatment and tell your doctor right away if you become pregnant.

Your Megace dose may need to change if you undergo surgery, are ill, come under stress, or have an infection. Do not change your dose or schedule without first consulting with your doctor.

To ensure your safety in taking Megace, tell your doctor if you have ever had any of the following:

  • Diabetes
  • An adrenal gland disorder
  • A stroke or blood clot

Women with HIV or AIDS should not breastfeed because the virus may be passed through breast milk.

Some other drugs can interact with megestrol acetate and cause adverse reactions. Tell your doctor about all the medications you take, including over the counter medicine, vitamins, and herbal products, but especially any type of blood thinner.

Form and Strength

This appetite stimulant is available in tablet form.

Megace tablet strengths:

  • 40mg
  • 160mg

The 40mg Megace tablets are available in quantities of 100 while the 160mg tablets are available in quantities of 30, 90, and 100.


Can you take Megace to prevent weight loss?

Megace is not approved for preventing weight loss but to treat unexplained weight loss in those with acquired immunodeficiency syndrome. Megestrol acetate’s mechanism of action is unclear and should only be used when other possible causes of weight loss are ruled out.

How long does Megace stay in your system?

Megace has an elimination half-life approximately 20 to 50 hours. This means that megestrol acetate concentrations reduce by half in this amount of time and continue to do so until the drug is fully excreted. Your Megace dose should then be completely out of your system within a week, depending on your dose and metabolism.



Additional information

Brand Name:


Scientific Name:

Megestrol Acetate, Megestrol acetate

Other Names:

Magestrol, Megace, Megestrol


40mg, 160mg

Quantities Available:

30, 90, 100