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Nilstat oral suspension is a medication used to treat fungal infections of the mouth, such as oral thrush. Nilstat oral suspension contains the active ingredient nystatin, which is an antifungal that works by stopping the growth of fungus.

Use and Dosage

Use this medication as directed by your doctor, usually 4 times a day. Shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

Unless your doctor instructs you otherwise, use as follows: Place half of the dose in one side of the mouth. Swish it around the mouth, gargle, and swallow or spit out as directed. Keep the liquid in your mouth for as long as possible. Then repeat with the remaining half of the dose in the other side of the mouth. Avoid eating for 5 to 10 minutes after using this medication.

It may take from several days to several months to complete treatment. Use this medication regularly to get the most benefit from it. Remember to use it at the same time each day. The dosage is based on your medical condition and response to treatment.

Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow the infection to continue, resulting in a return of the infection.

Tell your doctor if your condition lasts after several days of treatment or if it gets worse.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using nystatin if you have mouth irritation.

Nystatin may cause serious side effects including:

  • Fast heart rate
  • Trouble breathing
  • Severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Common side effects of nystatin may include:

  • Mouth irritation
  • Upset stomach, nausea, vomiting, diarrhea
  • Skin rash

This is not a complete list of side effects and others may occur.


  • Before taking nystatin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: HIV disease, diabetes, kidney disease.
  • This product contains sugar. Caution is advised if you have diabetes. Ask your doctor or pharmacist about the safe use of this product.
  • Denture wearers need to be careful to properly clean and maintain their dentures during treatment with this medication.
  • Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
  • During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.
  • It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Forms and Strengths

Nilstat Oral Suspension is available in the following forms and strengths:

  • Nystatin Suspension:
    • 100000u/1mL


What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while taking nystatin?

Do not use nystatin to treat any condition that has not been checked by your doctor.

What other drugs will affect nystatin?

Other drugs may affect nystatin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.



Additional information