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Osteo Bi-Flex Gold is a dietary supplement designed to support joint health. It contains a combination of ingredients such as glucosamine, chondroitin, MSM (methylsulfonylmethane), and 5-Loxin AdvancedTM.

Use and Dosage

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use Osteo Bi-Flex, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Do not use different formulations of chondroitin and glucosamine at the same time without medical advice. Using different formulations together increases the risk of an overdose of chondroitin and glucosamine.

If you need surgery or dental work, stop taking Osteo Bi-Flex at least 2 weeks ahead of time.

Call your doctor if the condition you are treating with Osteo Bi-Flex does not improve, or if it gets worse while using this product.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although not all side effects are known, Osteo Bi-Flex is thought to be safe when taken for up to 2 years.

Stop using Osteo Bi-Flex and call your healthcare provider at once if you have:

  • Irregular heartbeats
  • Swelling in your legs

Common side effects of Osteo Bi-Flex may include:

  • Nausea, diarrhea, constipation
  • Stomach pain, gas, bloating
  • Hair loss
  • Puffy eyelids

This is not a complete list of side effects and others may occur.


  • Glucosamine can slightly elevate liver enzymes, which can be a concern for individuals with liver disease.
  • Glucosamine can increase eye pressure, so individuals with glaucoma should consult their doctor before using Osteo Bi-Flex.
  • Osteo Bi-Flex contains glucosamine derived from shellfish, so individuals with severe shellfish allergies should avoid it.
  • MSM, one of the ingredients in Osteo Bi-Flex, can increase swelling and pain in individuals with chronic venous insufficiency.
  • Osteo Bi-Flex, specifically the ingredients MSM, Boswellia serrata, glucosamine, and chondroitin, can interact with blood thinners like Coumadin (warfarin), leading to easy bruising and bleeding.

Forms and Strengths

Osteo Bi-Flex Gold is available in the following forms and strengths:

  • Osteo Bi-Flex Gold Caplet:
    • 2400 mg


What are the benefits of taking Osteo Bi-Flex Gold?

Glucosamine and chondroitin are believed to support joint health and potentially alleviate osteoarthritis pain. However, note that the use of glucosamine and chondroitin lacks proven benefit.

What happens if I miss a dose?

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra Osteo Bi-Flex to make up for the missed dose.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while taking Osteo Bi-Flex?

Follow your healthcare provider’s instructions about any restrictions on food, beverages, or activity.



Additional information