Safely Buy Otezla ( Apremilast ) from Canada Prescriptions Plus.

We don't sell this brand-version medication.

( Affordable Generic Alternatives )


Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Apremilast 10mg 60 $79.95 Add To Cart
Apremilast 20mg 60 $89.95 Add To Cart
Apremilast 30mg 90 $105.95 Add To Cart
Dosage: 10mg
Quantity: 60
Price: $79.95
Dosage: 20mg
Quantity: 60
Price: $89.95
Dosage: 30mg
Quantity: 90
Price: $105.95


Otezla is an anti-inflammatory medication used to treat psoriasis including psoriatic arthritis, plaque psoriasis, and Behcet’s disease.

Apremilast is a small molecule phosphodiesterase 4 inhibitor that acts within your cells to reduce inflammation and increase your levels of cyclic adenosine monophosphate (cAMP). Thanks to these actions, Otezla helps treat moderate to severe plaque psoriasis and psoriatic arthritis.

This psoriasis medication is an effective form of treatment that has been found to greatly improve symptoms in specific sites such as nail and scalp psoriasis, pruritis, and quality of life.

Uses and Dosage

The dose of Otezla that is prescribed will vary depending on the individual and psoriatic condition being treated. Follow all your doctor’s instructions and read packaging labels carefully to ensure the best results.

  • Swallow tablet whole, do not crush or chew
  • Take with or without food
  • An initial dose of 10mg is titrated within the first 5 days of treatment
  • Most adults take 30mg twice daily
  • Those with renal impairment should only take 30mg once daily
  • Store at room temperature away from moisture and heat

Side Effects

Otezla may cause some side effects to develop while it reduces inflammation and improves psoriatic symptoms. Speak with your doctor for more specific information regarding any symptoms you may encounter when taking apremilast.

Common Otezla side effects:

  • Nausea, diarrhea
  • Headache
  • Cold symptoms (stuffy nose, sneezing, sore throat)

Serious Side Effects

Some more serious side effects may occur when taking apremilast. Stop using Otezla and call your doctor right away if you notice any of the following symptoms:

  • Severe diarrhea, nausea, and vomiting
  • Significant or unexplained weight loss
  • Changes in mood, new or worsening depression
  • Thoughts of suicide or hurting yourself

Allergic Reactions

Do not take Otezla if you are allergic to apremilast or any of the tablet’s listed ingredients. If you develop an allergic reaction, stop using the medication and contact your doctor.

Otezla allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


Some people may have suicidal thoughts when taking Otezla. Monitor changes in your mood or symptoms and report them to your doctor.

To ensure Otezla is safe for you to take, tell your doctor if you have ever had any of the following:

  • Kidney disease
  • Depression or suicidal thoughts or actions

Some drugs may interact with apremilast and cause adverse reactions. To ensure your safety and the efficacy of all your medications, tell your doctor about everything you take, including over the counter medicine, vitamins, and herbal products, but especially any of the following:

  • Carbamazepine
  • Enzalutamide
  • Fosphenytoin
  • Mitotane
  • Phenytoin
  • Primidone
  • Rifabutin
  • Rifampin
  • Rifapentine
  • St John’s Wort
  • Tofacitinib

Apremilast may cause harm to an unborn baby if used during pregnancy. Ensure that you use effective birth control while taking Otezla and tell your doctor right away if you become pregnant.

Breastfeeding while taking Otezla may not be safe. Consult with your doctor about the risks to determine a personalized treatment plan.

Form and Strength

This psoriasis medication is available in tablet form.

Otezla tablet strength:

  • 30mg

The 30mg Otezla tablets are available in quantities of 90.


Does Otezla cause weight gain?

No, Otezla is not expected to cause you to gain weight during treatment. In fact, you are more likely to lose weight while taking apremilast according to studies. While reducing inflammation, this medication can lead to small fluctuations and decreases in weight.

What does Otezla do to the body?

Otezla uses apremilast, a phosphodiesterase 4 inhibitor, to reduce inflammation throughout your body by increasing the levels of cyclic adenosine monophosphate within your cells. Thanks to this action, Otezla can modify your immune system and through this reduce symptoms related to various psoriatic conditions.



Additional information

Brand Name:


Scientific Name:


Other Names:



10mg, 20mg, 30mg

Quantities Available:

60, 90