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Parlodel is a prolactin inhibitor used to treat hyperprolactinemia, a hormone imbalance where too much prolactin is produced in the blood. This medication is also sometimes used with surgery or radiation to treat acromegaly, a condition caused by a pituitary gland that produces too much growth hormone.

Bromocriptine is a sympatholytic dopamine D2 receptor antagonist that lowers prolactin production through its inhibitory actions on dopamine receptors. Parlodel may also offer antitumoral effects caused by too much prolactin.

This hormone medication is an effective treatment for hyperprolactinemia that is generally well tolerated. Parlodel has been found to facilitate pregnancy in women with this condition and causes no teratogenic effect in mother or child.

Uses and Dosage

The dose of Parlodel that is prescribed will vary depending on the individual and prolactin condition being treated. Follow all your doctor’s instructions and read packaging labels carefully to ensure the best results.

  • Swallow tablets whole
  • Take with food, even if taken before bed
  • Most adults take an initial dose of 1.25 to 2.5mg once a day
  • Doses can increase by 2.5mg every 2 to 7 days until a response is achieved
  • Hyperprolactinemia maintenance doses can range from 2.5mg to 15mg once daily
  • For acromegaly, maintenance doses range from 20 to 30mg
  • Adults should not take more than 100mg a day to treat acromegaly
  • You will need frequent checkups during treatment
  • Do not suddenly stop taking Parlodel
  • Store at room temperature away from moisture, heat, and light
  • Keep bottle tightly closed and away from children and pets

Side Effects

Parlodel may cause some side effects to develop while affecting the chemicals in your brain and your body’s production of prolactin. Speak with your doctor for more information regarding any symptoms that you may encounter when taking bromocriptine.

Common Parlodel side effects:

  • Dizziness
  • Headache
  • Hallucinations
  • Nausea, constipation
  • Abnormal involuntary movements

Serious Side Effects

Some more serious adverse reactions may occur when taking bromocriptine. Stop using Parlodel and call your doctor right away if you develop any of the following side effects:

  • Numbness, pain, paleness, or discolouration in your fingers or toes
  • Vision problems, constant runny nose
  • Chest pain, pain when you breathe, fast hear rate, rapid breathing, shortness of breath
  • Back pain, swelling in ankles or feet, urinating less than usual
  • Confusion, hallucinations, feeling like you might pass out
  • Uncontrollable muscle movements, loss of balance or coordination
  • Bloody or tarry stools, coughing blood, vomit that looks like coffee grounds

Bromocriptine may cause you to fall asleep during daytime activities including working, talking, eating, or driving, even after feeling alert. Tell your doctor if you have any issues with daytime sleepiness.

Allergic Reactions

Do not use Parlodel if you are allergic to bromocriptine or an ergot medicine like dihydroergotamine, ergotamine, ergonovine, or methylergonovine. If you develop an allergic reaction, stop taking this medication and contact your doctor.

Parlodel allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat

Parlodel tablets may contain lactose. Tell your doctor if you have a hereditary form of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption before taking this medication.


Do not use Parlodel if you have any of the following:

  • Uncontrolled high blood pressure
  • High blood pressure caused by pregnancy
  • If you have recently had a baby
  • History of coronary artery disease or severe heart disease

Bromocriptine may cause you to fall asleep suddenly, even after feeling alert. Avoid driving or performing any hazardous tasks that require alertness until you know how this medication will affect you.

Avoid drinking alcohol while taking Parlodel because it can cause an increase in side effects.

To ensure your safety when taking Parlodel, tell your doctor if you have ever had any of the following:

  • High or low blood pressure, heart disease, heart attack
  • Liver or kidney disease
  • Pituitary gland tumour
  • Stomach ulcer, stomach or intestinal bleeding
  • Mental illness or psychosis

You may need to stop using Parlodel if you become pregnant during treatment. Consult with your doctor to determine the best treatment plan for you.

If you are not taking Parlodel to normalize your menstrual cycle and increase your chances of becoming pregnant, use a barrier form of birth control to prevent pregnancy during treatment.

Do not breastfeed while taking Parlodel.

Certain migraine medications may be less effective when taken alongside bromocriptine. Wait 6 hours before or after taking Parlodel if you also take an ergot headache medicine.

Some drugs may interact with bromocriptine and cause unwanted side effects. To avoid adverse reactions, tell your doctor about all the medications you take, including over the counter medicine, but especially the following:

  • Migraine medication
  • Medicine to treat infections
  • Antipsychotic medication
  • Medicine to treat Parkinson’s disease
  • Restless leg syndrome medication
  • Other medication for acromegaly

Tell your doctor if you use any of the following types of medications:

  • Antidepressants, sedatives, opioid medications
  • Medicines to treat psychiatric disorders
  • Antibiotic or antifungal medications
  • Anti-malaria drugs
  • Asthma or allergy medication
  • Cancer medicine, medication to prevent organ transplant rejection
  • Cholesterol-lowering drugs
  • Oral diabetes medication
  • Heart or blood pressure medications, heart rhythm medication
  • HIV or AIDS medication
  • Seizure medications
  • Sildenafil and other medicines to treat erectile dysfunction
  • Stomach acid reducers

Parlodel should not be given to any child under the age of 11.

Form and Strength

This prolactin medication is available in tablet form.

Parlodel tablet strengths:

  • 2.5mg
  • 5mg

The 2.5 and 5mg tablets are both available in quantities of 100 while the 2.5mg ones are also available in quantities of 90.


What to avoid when taking Parlodel?

You should avoid driving or performing any hazardous activities until you know how Parlodel will affect you because it can impair your reactions. During treatment you should also avoid drinking alcohol because it can increase adverse reactions. Speak with your doctor to learn more about what medications and activities you should avoid while taking Parlodel.

Can Parlodel restore ovulation?

Women whose menstrual cycles have been altered due to an excess in prolactin levels can rebalance their menstruation and ovulation with Parlodel treatment. This is because bromocriptine helps decrease prolactin production. Many women with hyperprolactinemia use Parlodel to normalize their cycle and improve their chances of getting pregnant.



Additional information

Brand Name:


Scientific Name:


Other Names:

Bromocriptine, Parlodel, Sicriptin


2.5mg, 5mg

Quantities Available:

90, 100


Capsule, Tablet