Pertzye
Prescription Required
Indications
Pertzye is a prescription medication used to treat exocrine pancreatic insufficiency (EPI) in individuals with cystic fibrosis (CF). EPI is a condition where the pancreas does not produce enough enzymes to properly digest food.
Pertzye contains a mixture of enzymes, including lipases, proteases, and amylases, which help break down fats, proteins, and carbohydrates in the digestive system.
Use and Dosage
Some brands of this medication have a Medication Guide provided by your pharmacist. If one is available, read the Medication Guide before you start taking this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with meals and snacks as directed by your doctor. Swallow the capsule whole. Do not crush or chew the capsules or keep the capsules in your mouth. Doing so can irritate the mouth and change the way the medication works.
If swallowing is difficult, then the capsule may be opened and the contents mixed in a small amount of liquid or soft food that does not need to be chewed (such as room-temperature applesauce). Do not mix the contents of the capsule with alkaline food or liquid (such as milk, ice cream, or tea). Consult your doctor or pharmacist for more information about what foods/liquids (such as infant formula, and breast milk) to avoid when mixing. Swallow the food or liquid right away, making sure not to chew the medication. Drink a glass of water or juice after swallowing the food to make sure all the medication is swallowed. Do not save the medication mixture for later.
Dosage is based on your medical condition, diet, weight, and response to treatment. Do not take more capsules in a day than prescribed by your doctor. Your condition will not improve any faster, and your risk of side effects will increase.
Drink plenty of fluids while taking this medication unless your doctor tells you otherwise.
Use this medication regularly to get the most benefit from it. Take it with every meal or snack.
If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication.
Do not change brands or dosage forms of pancrelipase without consulting your doctor or pharmacist. Different products may contain different amounts of digestive enzymes.
Side Effects
Pertzye may cause serious side effects, including:
- Irritation of the inside of your mouth. This can happen if Pertzye is not swallowed completely.
- Increase in blood uric acid levels. This may cause worsening of swollen, painful joints (gout) caused by an increase in your blood uric acid levels.
- Allergic reactions include trouble breathing, skin rash, itching, or swollen lips.
Call your doctor right away if you have any of these symptoms.
The most common side effects of Pertzye include:
- Diarrhea
- Upset stomach (indigestion)
- Cough
Other side effects:
Pertzye and other pancreatic enzyme products are made from the pancreas of pigs, the same pigs people eat as pork. These pigs may carry viruses. Although it has never been reported, it may be possible for a person to get a viral infection from taking pancreatic enzyme products that come from pigs.
Tell your doctor if you have any side effects that bother you or do not go away.
These are not all of the possible side effects of Pertzye. For more information, ask your doctor or pharmacist.
Cautions
- Before taking pancrelipase, tell your doctor or pharmacist if you are allergic to it; or pork protein; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
- Before using this medication, tell your doctor or pharmacist your medical history, especially of: sudden/severe swelling of the pancreas (acute pancreatitis), sudden worsening of long-term disease of the pancreas, gout, kidney disease, high uric acid level in the blood (hyperuricemia), and intestinal problems (such as blockage).
- If you have diabetes, pancrelipase may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
- Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
- During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.
- It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
Forms and Strengths
Pertzye is available in the following forms and strengths:
- Pertzye DR Capsule:
- 4000/14375/15125 units
FAQ
How is Pertzye taken?
Pertzye is taken orally in the form of delayed-release capsules. The dosage recommendations are based on lipase units, and it is important to follow the dosage instructions provided by your healthcare provider.
What are the common side effects of Pertzye?
Common side effects of Pertzye may include stomach pain, diarrhea, constipation, and gas. It is important to discuss any potential side effects and concerns with your healthcare provider.
Are there any alternatives to Pertzye?
Yes, there are other pancreatic enzyme replacement therapies (PERT) available for the treatment of EPI, such as Creon, Pancreaze, Zenpep, Ultresa, and Viokace. These medications work similarly to Pertzye to improve digestion.
Resources:
Additional information
Brand Name: |
Pertzye |
|---|---|
Scientific Name: |
Lipase/Protease/Amylase |
Other Names: |
Pertzye |
Strength(s): |
4000/14375/15125units |
Quantities Available: |
100 |
Formulation: |
Delayed Release Capsule |
