Safely Buy Polytrim ( Polymixin/trimethoprim ) from Canada Prescriptions Plus.

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Polytrim is an eye medication used to treat eye infections caused by bacteria.

This ophthalmic medication combines polymyxin with trimethoprim to interrupt the metabolic pathway of bacterial cells and disrupt the structure of their membrane. These actions allow Polytrim to treat infections in your eyes when applied topically because it kills bacteria.

These eye drops have been found to be an effective and safe method of treatment for eye infections. When applied topically, Polytrim helps treat infections and kill bacteria without causing many adverse reactions.

Uses and Dosage

The dose and usage of Polytrim prescribed will vary depending on the individual and infection being treated. Follow all your doctor’s instructions and read packaging labels carefully for the best results.

  • Wash hands thoroughly before and after application
  • Most adults apply Polytrim every 3 hours for 7 to 10 days
  • To apply, tilt back your head and pull down your lower eyelid
  • Hold the dropper above your eye, look up and away, and squeeze a drop into the pocket you created with your eyelid.
  • Gently press a finger to the inside corner of your eyes for one minute to prevent the solution from draining into your tear duct
  • Close your eyes for 2 to 3 minutes after application and tilt your head down
  • Do not touch the eye dropper or place it directly onto your eye to avoid contamination
  • Remove contact lenses before applying Polytrim and wait 15 minutes before reinserting them
  • Only use other eye medications if directed by your doctor
  • Do not use Polytrim if the liquid has changed colours or contains particles
  • Use Polytrim for the entire length of time prescribed, even if symptoms have improved
  • Contact your doctor if symptoms persist past 7 days
  • Store at room temperature with the lid tightly closed away from moisture, heat, and light
  • Keep away from children and pets

Side Effects

Polytrim may cause some side effects to develop while fighting bacterial infections in your eyes. Speak with your doctor for more information regarding any symptoms that you may experience while using polymyxin and trimethoprim.

Common Polytrim side effects:

  • Mild burning, stinging, or itching after application

Serious Side Effects

Some more serious adverse reactions may occur when using polymyxin and trimethoprim. Stop using these Polytrim eye drops and call your doctor if you develop any of the following side effects:

  • Eye pain, swelling, redness, or severe discomfort
  • Crusting or drainage
  • Eyelid swelling or redness
  • New or worsening symptoms of infection

Allergic Reactions

Do not use Polytrim if you are allergic to polymyxin B, trimethoprim, or any of the other listed eye drop components.

If you notice signs of an allergic reaction, stop using these eye drops and contact your doctor.

Polytrim allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


Tell your doctor if you are pregnant or breastfeeding before taking Polytrim to monitor your condition and that of your child.

Do not apply Polytrim eye drops while wearing contact lenses because a preservative in the solution could cause your lenses to stain. Wait at least 15 minutes before putting your contact lenses in after using these eye drops.

Do not use any other eye medications during your Polytrim treatment unless directed to do so by your doctor.

Some other drugs may interact with polymyxin or trimethoprim and cause adverse reactions. To avoid this, tell your doctor about all the medications you take, including any over the counter medicines, vitamins, or herbal products.

Do not administer this medication to any child who is younger than 2 months old.

Form and Strength

This eye infection medication is available in eye drop form.

The Polytrim eye drops are available in volumes of 10ml.


How many times a day can you use Polytrim eye drops?

You can apply this ophthalmic medication multiple times each day. Polytrim eye drops are designed to treat bacterial eye infections and are recommended to be applied every 3 hours for a period of 7 to 10 days.

What are the warnings for Polytrim?

Polytrim is generally safe and well-tolerated with a low incidence of adverse events. Allergic reactions pose the most threat and are rare among the eye drop users. If you wear contact lenses, ensure that you do not apply these eye drops while wearing them because they could become discoloured or stained.



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