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Progesterone Injection

Prescription Required
Formulation : Solution for Injection
Drug Name Dosage Quantity Price Buy Now
Progesterone Injection 50mg/1mL 10mL $84.70 Add To Cart
Progesterone Injection
Dosage: 50mg/1mL
Quantity: 10mL
Price: $84.70


Progesterone Injection is a hormone medication used to cause menstrual periods in premenopausal women who lack progesterone. The drug is also used to prevent overgrowth in the uterine lining of women undergoing estrogen replacement therapy.

Progesterone is a natural hormone essential for the regulation of ovulation and menstruation. This hormone offers luteal support and endometrium protection to stimulate menstrual periods and support fertility. When injected, progesterone helps regulate your menstrual cycle and support early pregnancy.

This hormone medication is an effective method for controlling and regulating the menstrual cycle of premenopausal women. Progesterone helps protect your endometrium while supporting ovulation and pregnancy without causing adverse cardiovascular events or severely increasing your risk of breast cancer.

Uses and Dosage

The dose of progesterone prescribed will vary depending on the individual being treated. Follow all your doctor’s instructions and read packaging labels carefully to ensure the best therapeutic results.

  • Progesterone is administered intramuscularly
  • Slight irritation at injection site is common
  • To stimulate menstrual periods, most women take 5 to 10mg for 6 to 8 days
  • Withdrawal bleeding should occur within 48 to 72 hours after the last injection
  • To treat uterine bleeding, women take 5 to 10mg daily for 6 days
  • Uterine bleeding should stop within six days
  • When taking estrogen, progesterone is usually started two weeks after estrogen therapy
  • Progesterone injections should be discontinued if a menstrual flow begins
  • Do not use if the injection solution has particulate matter or if it is discoloured
  • Store at room temperature away from children and pets
  • Do not let the progesterone injection solution freeze

Side Effects

Progesterone injections may cause some side effects to develop while regulating your hormone levels to support proper menstruation. Speak with your doctor for more information regarding any symptoms that you may encounter when taking progesterone.

Common progesterone injection side effects:

  • Drowsiness, dizziness
  • Breast pain
  • Mood changes
  • Headache
  • Constipation, diarrhea, heartburn
  • Bloating, swelling in hands or feet
  • Joint pain
  • Hot flashes
  • Vaginal discharge

Serious Side Effects

Some more serious adverse reactions may occur when taking progesterone. Stop using this medication and contact your doctor right away if you notice any of the following side effects:

  • Unusual vaginal bleeding
  • Pain or burning when you urinate
  • Breast lump
  • Sudden vision problems, severe headache, pain behind your eyes
  • Symptoms of depression (insomnia, weakness, mood changes)
  • Severe dizziness, drowsiness, spinning sensation, confusion, shortness of breath
  • Heart attack symptoms (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating)
  • Liver problems (nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-coloured stools, jaundice)
  • Signs of a stroke (sudden numbness or weakness, sudden severe headache, slurred speech, problems with speech or balance)
  • Signs of a blood clot in your lung (chest pain, sudden cough, wheezing, rapid breathing, coughing blood)
  • Signs of a blood clot in your leg (pain, swelling, warmth, or redness in one or both legs)

Allergic Reaction

Progesterone is a naturally occurring hormone and so anyone can take it; however, you may have an allergic reaction to another component in the injection solution. Peanut oil may be used in some formulations of this progesterone injection solution. If you develop signs of an allergic reaction, stop using progesterone and call your doctor.

Progesterone injection allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


Do not use progesterone while pregnant without first consulting your doctor. The hormone could cause harm to an unborn baby if used incorrectly. Use effective birth control and tell your doctor right away if you become pregnant during treatment.

Progesterone may impair your thinking or reactions; be careful when driving or performing any tasks that require alertness, especially until you know how the injections will affect you.

Do not use progesterone if you have any of the following:

  • Abnormal vaginal bleeding
  • History of breast cancer
  • Liver disease
  • Recent heart attack, stroke, or blood clot

Progesterone is not designed to prevent heart disease or dementia and may increase your risk of developing these conditions.

Progesterone injections may increase your risk of blood clots, stroke, heart attack, or breast cancer.

Some formulations of this progesterone injection may contain peanut oil; do not use this medication without telling your doctor if you are allergic to peanuts.

To ensure your safety when taking progesterone, tell your doctor if you have any of the following:

  • Heart disease, circulation problems
  • Migraines
  • Asthma
  • Kidney disease
  • Seizures or epilepsy
  • History of depression
  • Risk of developing coronary artery disease

Tell your doctor if you are breastfeeding before using progesterone; the hormone can pass into your breastmilk and may affect your nursing baby.

Some drugs may interact with your progesterone injections and cause adverse effects. To avoid this, tell your doctor about all the medications that you take, including over the counter medicines, vitamins, and herbal products.

Form and Strength

This hormone medication is available in the form of injection solution.

Progesterone injection solution strength:

  • 50mg/ml

The progesterone injection solution is available in volumes of 10ml.


What to expect after progesterone injection?

Progesterone injections may cause some slight pain or swelling at the site of injection followed by some minor side effects of the hormone therapy. These reactions are usually well-tolerated and include tender breasts, nausea, and drowsiness.

What not to do when taking progesterone?

You should avoid driving or performing hazardous tasks that require alertness during your progesterone injection therapy. Progesterone can cause you to become drowsy or tired and may impair your reactions. Assess your ability to perform these actions once you know how the progesterone injections will affect you.



Additional information

Brand Name:

Progesterone in Oil

Scientific Name:

Progesterone Injection

Other Names:

Progesterone in Oil



Quantities Available:



Solution for Injection