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Sodium Bicarbonate

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Sodium bicarbonate is a medication used to relieve and prevent heartburn and indigestion.

Sodium bicarbonate is a chemical compound that combats acidosis in your stomach by raising solution pH through an increase in plasma bicarbonate levels. This allows the medication to reduce and relieve heartburn as well as indigestion by reducing your levels of stomach acid.

This medication has many indications that may not be listed, but sodium bicarbonate is often prescribed to treat issues relating to excess stomach acid such as heartburn and indigestion.

Uses and Dosage

The dose prescribed for sodium bicarbonate will vary depending on the condition and individual being treated. Always follow your doctor’s instructions and read packaging labels carefully when taking any medication.

  • Dissolve tablets completely in water
  • For 325mg doses, adults should take 2 to 8 tablets every 4 hours
  • Adults up to 60 years old shouldn’t take more than 48 tablets in 24 hours
  • Adults over 60 shouldn’t take more than 24 tablets within 24 hours
  • For 650mg doses, adults should take 1 to 4 tablets every 4 hours
  • Adults under 60 shouldn’t take more than 24 tablets within 24 hours
  • Adults over 60 should take no more than 12 tablets in 24 hours
  • Do not take the maximum dose for longer than 2 weeks
  • Store at room temperature away from moisture

Side Effects

Sodium bicarbonate may cause some side effects to develop while it neutralizes your stomach acid. Speak with your doctor for more information regarding any symptoms you may encounter while taking sodium bicarbonate.

Common sodium bicarbonate side effects:

  • Dry mouth
  • Increased thirst
  • More frequent urination

Serious Side Effects

Some more serious side effects may occur when taking sodium bicarbonate. Stop taking this medication and call your doctor right away if you notice any of the following symptoms:

  • Severe stomach pain
  • Swelling, weight gain
  • Shortness of breath

Allergic Reactions

Do not take this antacid medication if you are allergic to sodium bicarbonate. If you develop signs of an allergic reaction, stop taking the medication and call your doctor immediately.

Sodium bicarbonate allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling in face, lips, tongue, or throat


If you regularly use other medications, do not use sodium bicarbonate without first consulting with your doctor to ensure no interactions occur.

Consult with your doctor before taking sodium bicarbonate if you follow a low-salt diet or if you have high blood pressure to ensure it is safe for you to take.

Before using sodium bicarbonate, tell your doctor about any medical conditions you have, especially the following:

  • Kidney disease
  • Liver disease
  • Heart disease
  • High blood pressure
  • If you are on a low salt diet

The effect of sodium bicarbonate during pregnancy is uncertain. This medication can cause fluid retention which can be dangerous during pregnancy. Do not take sodium bicarbonate while pregnant without first talking with your doctor.

Consult with your doctor before taking sodium bicarbonate while breastfeeding; it is unknown whether the medication will pass into breast milk or if it can harm a nursing child.

Other medications may interact with sodium bicarbonate to cause adverse reactions. Tell your doctor about all the medications you take, including over-the-counter medicines, vitamins, and herbal products.

Form and Strength

This antacid medication is available in tablet form.

Sodium bicarbonate tablet strength:

  • 325mg

The 325mg tablets are available in quantities of 1000.


How does Sodium Bicarbonate relieve heartburn?

Sodium bicarbonate is absorbed into your system and breaks down into its two forms, sodium and bicarbonate. These chemicals work to prevent heightened levels of acid in your stomach and the rest of your system by inhibiting excess hydrogen ion concentration. By reducing stomach acid, sodium bicarbonate helps relieve and prevent heartburn as well as indigestion and sour stomach.

Does sodium bicarbonate cause weight gain?

Like any medication, sodium bicarbonate can lead to some side effects. One side effect that may occur is weight gain; however, this symptom is less common. If you notice rapid weight gain, speak with your doctor. Generally, sodium bicarbonate is well tolerated and produces less interactions with other medications.



Additional information

Brand Name:

Sodium Bicarbonate

Scientific Name:

Sodium bicarbonate

Other Names:

Sodium Bicarbonate



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