Safely Buy Vagifem Vaginal Tablet ( Estradiol ) from Canada Prescriptions Plus.

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Vagifem Vaginal Tablet

Prescription Required
Formulation : Vaginal Tablet
Drug Name Dosage Quantity Price Buy Now
Vagifem Vaginal Tablet 10mcg 24 $55.10 Add To Cart
Vagifem Vaginal Tablet
Dosage: 10mcg
Quantity: 24
Price: $55.10


Vagifem (estradiol) is a medication approved for the treatment of atrophic vaginitis, a condition that occurs due to menopause. It replaces the estrogen that the body is no longer producing, and helps alleviate symptoms such as vaginal dryness, itching, and burning.

Uses and Dosage

Before using Vagifem, carefully read the Patient Information Leaflet provided by your pharmacist.

Use Vagifem as directed by your physician, typically once daily for the first 2 weeks, then 2 times a week thereafter.

The dosage will be based on your individual medical condition and response to treatment, it should be used regularly to obtain the maximum benefit from it.

Do not increase the dosage or use Vagifem more frequently or for an extended period than directed. This may lead to the development of adverse effects.


  • Remove an applicator from the packaging and discard the plastic wrapping before using Vagifem
  • Ensure hands are clean and dry before handling the applicator
  • Grasp applicator and position finger on plunger
  • Select a comfortable position for vaginal insertion, such as reclining or standing
  • Gently guide applicator through vaginal opening without applying force
  • If insert falls out of applicator before insertion, discard both insert and applicator and use a new one
  • Insert applicator as far as comfortably possible, or until half of applicator is inside vagina, whichever is less
  • Gently press plunger until it is fully depressed, releasing insert into vagina
  • Insert will dissolve over several hours
  • Gently remove applicator and discard as you would a plastic tampon applicator
  • Insertion may be done at any time of the day, it is recommended to use the same time daily for all applications of Vagifem vaginal inserts
  • Consult with your healthcare provider or pharmacist if you have any questions.

Side Effects

Common side effects of Vagifem vaginal tablets may include:

  • Headache
  • Breast tenderness
  • Nausea
  • Diarrhea
  • Bloating
  • Weight changes

Serious side effects of Vagifem vaginal tablets may include:

  • Mood changes
  • Unusual vaginal bleeding
  • Increased vaginal irritation/itching/odor/discharge
  • Stomach/abdominal pain
  • Yellowing eyes/skin
  • Dark urine
  • Swelling hands/ankles/feet
  • Increased thirst/urination
  • Persistent nausea/vomiting

Vagifem may have serious and rare risks associated with blood clots such as heart attacks, stroke, deep vein thrombosis, and pulmonary embolism. Seek immediate medical attention if you experience any serious side effects, including:

  • Chest, jaw or left arm pain
  • Unusual sweating
  • Sudden or severe headache
  • Weakness or numbness on one side of the body
  • Confusion
  • Difficulty speaking
  • Sudden vision changes (such as partial or complete blindness)
  • Pain, redness or swelling of legs
  • Tingling, weakness, or numbness in the arms or legs
  • Difficulty breathing
  • Coughing up blood
  • Sudden dizziness or fainting

Inform your healthcare provider if you experience any severe or unexpected side effects.


Inform healthcare provider or pharmacist of any known allergies prior to initiation of estradiol therapy.

Inquire with the pharmacist regarding any potential allergic reactions from inactive ingredients.

Avoid smoking and use of tobacco products during estradiol therapy. Smoking tobacco increases the risk of thromboembolic events, hypertension and myocardial infarction.

Inform the treating healthcare provider of any recent surgery or prolonged immobilization as it increases the risk of thromboembolic events.

Estradiol therapy may result in pigmentation changes such as Melasma, which may worsen with sun exposure. To minimize this effect, it is recommended to limit sun exposure, avoid tanning beds and lamps, and use sunscreen and protective clothing when outdoors.

Consult a treating healthcare provider for any necessary precautions or temporarily cessation of treatment.

Form and Strength

You can order this medication in the following forms and strengths:

Vagifem vaginal tablets:

  • 10mcg
  • 25mcg


How long does it take for Vagifem to dissolve?

The dissolution time of Vagifem insert can vary, but typically takes several hours, and may extend beyond 24 hours.

Should I take Vagifem in the morning or at night?

Vagifem may be administered at any convenient time, but it is recommended to maintain a consistent administration schedule to optimize treatment.



Additional information

Brand Name:

Vagifem Vaginal Tablet

Scientific Name:


Other Names:

Vagifem Vaginal Tablet



Quantities Available:



Vaginal Tablet