Safely Buy Vimovo ( Naproxen/Esomeprazole Magnesium ) from Canada Prescriptions Plus.

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Formulation : Modified Release Tablets
Drug Name Dosage Quantity Price Buy Now
Vimovo 375/20mg 60 $94.70 Add To Cart
Vimovo 500/20mg 60 $94.70 Add To Cart
Vimovo 500/20mg 180 $265.10 Add To Cart
Dosage: 375/20mg
Quantity: 60
Price: $94.70
Dosage: 500/20mg
Quantity: 60
Price: $94.70
Dosage: 500/20mg
Quantity: 180
Price: $265.10


Vimovo is a pain reliever used to relieve symptoms of arthritis in adults and juvenile idiopathic arthritis in adolescents.

This medication combines naproxen, a nonsteroidal anti-inflammatory drug (NSAID), with esomeprazole magnesium, a proton pump inhibitor (PPI) to reduce pain with less risk of developing stomach ulcers. Naproxen inhibits substances in your body that lead to inflammation, pain, and fever, while esomeprazole decreases your production of stomach acid to reduce your risk of stomach ulcers that could develop from using naproxen.

Thanks to the actions of both drugs used in Vimovo, this medication can provide effective pain relief for a variety of arthritis conditions including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Dosage and Administration

The dose of Vimovo that is prescribed will vary depending on the individual and severity of arthritis being treated. Follow all your healthcare provider’s instructions and read packaging labels carefully to ensure the best results during treatment. Do not change your dose on your own.

  • Swallow tablets whole
  • Take at least 30 minutes before a meal
  • Use the lowest effective dose for the shortest amount of time needed
  • Adults should take one tablet twice daily
  • Doses can range from 375mg naproxen/20mg esomeprazole to 500mg naproxen/20mg esomeprazole twice a day
  • Children with juvenile arthritis who weigh more than 50kg should take the recommended adult dosing
  • Children weighing 38kg up to 50kg should take no more than 375mg naproxen/20mg esomeprazole twice a day
  • Store at room temperature away from children and pets

Side Effects

Vimovo may cause some side effects to develop while reducing your pain. Speak to your healthcare provider to learn more about any symptoms you may have during treatment.

Common Vimovo side effects:

  • Stomach discomfort
  • diarrhea

Serious Side Effects

Some more serious adverse effects may occur during treatment with Vimovo. Call your healthcare provider right away if you develop any of the following symptoms:

  • Severe stomach pain
  • Watery or bloody diarrhea
  • Bloody or tarry stools, coughing blood, vomit that looks like coffee grounds
  • Heart problems (swelling, rapid weight gain, shortness of breath)
  • Kidney issues (fever, rash, nausea, decreased appetite, joint pain, urinating less, blood in your urine, weight gain)
  • Liver problems (decreased appetite, stomach pain, dark urine, jaundice)
  • Low magnesium levels (dizziness, fast or irregular heartbeats, tremors, jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling)
  • Low red blood cell count (pale skin, unusual tiredness, light-headedness, shortness of breath, cold hands or feet)
  • New or worsening lupus symptoms (joint pain, skin rash on your cheeks or arms that gets worse under sunlight)

Seek immediate medical attention if you have any signs of a heart attack or stroke while taking Vimovo. Symptoms include chest pain spreading to your shoulder or jaw, sudden numbness or weakness, slurred speech, and shortness of breath.

Allergic Reactions

Do not use Vimovo if you are allergic to naproxen, esomeprazole, or any other NSAID. Stop using this medication and contact your healthcare provider right away if you notice any of the following signs of an allergic reaction:

  • Hives
  • Difficulty breathing
  • Sneezing, runny or stuffy nose
  • Wheezing
  • Swelling of face or throat
  • Fever
  • Sore throat
  • Burning eyes, skin pain
  • Red or purple rash
  • Blistering or peeling skin


  • Do not take Vimovo if you have had any of the following:
    • Recent or upcoming heart bypass surgery
    • Breathing problems
    • Kidney problems
    • Asthma attack or severe allergic reaction to aspirin or another NSAID
    • If you also take HIV medication that contains rilpivirine
  • To ensure your safety when taking Vimovo, tell your healthcare provider if you have ever had any of the following:
    • Heart disease
    • High blood pressure
    • Asthma
    • Crohn’s disease
    • Ulcerative colitis
    • Inflammatory bowel disease
    • Stomach or intestinal bleeding after taking an NSAID
    • Liver or kidney disease
    • Low magnesium levels
  • Treatment with Vimovo may increase your risk of developing a fatal heart attack or stroke, even if you have no risk factors before treatment. Do not use this medication immediately before or after undergoing heart bypass surgery.
  • Naproxen could cause you to have stomach or intestinal bleeding which can be fatal. Call your healthcare provider right away if you notice any of the following signs: black, bloody, or tarry stools, coughing blood, or vomit that looks like coffee grounds.
  • If you experience diarrhea that is watery or contains blood during treatment with Vimovo, contact your healthcare provider because it may indicate an infection.
  • Vimovo may cause you to develop new or worsening lupus symptoms. Tell your healthcare provider immediately if you notice any joint pain with a skin rash on your cheeks or arms that worsens under sunlight.
  • If you take Vimovo long term or more than once a day, you may be at an increased risk of breaking a bone.
  • Do not use Vimovo if you are pregnant unless your healthcare provider tells you to do so. Using any NSAID during the last 20 weeks of pregnancy could cause serious complications in your baby and pregnancy.
  • Ask your healthcare provider before breastfeeding while taking Vimovo because the medication may affect your nursing child.
  • Consult with your healthcare provider before taking any other medications to treat pain, fever, swelling, or cold/flu symptoms because they can contain similar ingredients.
  • When using Vimovo long-term, you may develop stomach growths called fundic gland polyps. Speak with your healthcare provider to discuss your risks and learn about symptoms.
  • You may develop a vitamin B-12 deficiency if you take Vimovo for longer than 2 years. Discuss ways to manage this condition if it occurs with your healthcare provider.
  • Some drugs can interact with Vimovo and cause adverse reactions. Tell your healthcare provider about all the medicines you take, including over the counter medications, but especially the following:
    • Other medications that contain naproxen
    • Other non-aspirin NSAIDs
    • Clopidogrel
    • St. John’s wort
    • Rifampin
    • Aspirin
    • Antihypertensive medications
    • Diuretic medicines
    • Antiretrovirals such as rilpivirine, atazanavir, and nelfinavir
    • Cilostazol
    • Digoxin
    • Lithium
    • Methotrexate
    • Cyclosporine
    • Tacrolimus
    • Diazepam
  • Vimovo is not an approved treatment for anyone under the age of 12 or who weighs less than 38kg.

Form and Strengths

This pain reliever is available in the form of modified release tablets.

  • Vimovo tablet strengths:
    • 375mg naproxen/20mg esomeprazole
    • 500/20mg

The 375/20mg and 500/20mg Vimovo tablets are both available in quantities of 60 while the 500/20mg tablets are also available in quantities of 180.


How should I take Vimovo?

Vimovo is recommended to be taken twice daily at least 30 minutes before a meal. Follow all your healthcare provider’s instructions when using this medication for the best therapeutic response. While the medication contains esomeprazole to reduce stomach acid production, you can also take antacids during treatment if needed.

What is Vimovo?

Vimovo is a combination medicine used to relieve pain from various types of arthritis in adults and children over 12 years old. The medication uses naproxen to reduce inflammation and pain while esomeprazole is added to.



Additional information

Brand Name:


Scientific Name:

Naproxen/Esomeprazole Magnesium

Other Names:



375/20mg, 500/20mg

Quantities Available:

60, 180


Modified Release Tablets