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Zetia, which is also known as ezetimibe, is clinically indicated as an adjunct to the patient’s diet for the reduction of elevated total cholesterol levels, low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) among adults diagnosed with primary hyperlipidemia.

Seek a healthcare provider’s guidance to appropriately assess individual patient conditions and determine the optimal use of this medication.

Use and Dosage

Read the Patient Information Leaflet if available from your pharmacist before you start taking ezetimibe each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily with or without food.

The dosage is based on your medical condition and response to treatment.

If taking a bile acid sequestrant (such as cholestyramine, or cholesterol), take ezetimibe at least 2 hours before or 4 hours after taking the bile acid sequestrant. These products may bind to ezetimibe, preventing your body from fully absorbing the drug.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Keep taking this medication even if you feel well. Most people with high cholesterol do not feel sick. It may take up to 2 weeks to get this drug’s full benefit.

Side Effects

Mild & Common Side Effects include:

  • Headache
  • Dizziness
  • Tired feeling
  • Stomach pain

Severe Side Effects include:

  • Severe abdominal pain
  • Signs of liver problems
  • Muscle pain
  • Severe fatigue

Note that this is not a full/complete list of the side effects of Zetia.

If you have severe or persistent side effects, stop taking the drug and get medical advice from your doctor or another healthcare expert.


Before taking ezetimibe, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of liver disease.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Form and Strengths

Zetia is available in the following form and strengths:

  • Zetia Tablet:
    • 10 mg
  • Ezetimibe Tablet:
    • 10 mg


What is the Zetia drug class?

This is classified as a lipid-lowering agent.

What must I do if I forget my Zetia dose?

If you forget your dosage for the day, take it right away, except if it is about time for your next dose.

Is it okay to cut Zetia in half?

Yes, you can cut the tablet in half. You may ask for assistance from a healthcare professional.

Does Zetia affect blood pressure?

Clinical trials show that Zetia does not affect blood pressure.

Can Zetia help in decreasing cardiovascular mortality and morbidity?

It is not determined yet whether this drug affects cardiovascular mortality and morbidity.

Can I use Zetia for a long time?

Yes, this drug is usually prescribed for long-term use.



Additional information

Brand Name:


Scientific Name:


Other Names:

Ezetimibe, Ezetrol



Quantities Available:

28, 84, 100, 168