Safely Buy Zylet ( Tobramycin/ Loteprednol etabonate ) from Canada Prescriptions Plus.

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Prescription Required
Formulation : Eye drops suspension
Drug Name Dosage Quantity Price Buy Now
Zylet 0.3%/0.5% 5mL $380.00 Add To Cart
Zylet 0.3%/0.5% 10mL $700.00 Add To Cart
Dosage: 0.3%/0.5%
Quantity: 5mL
Price: $380.00
Dosage: 0.3%/0.5%
Quantity: 10mL
Price: $700.00


Zylet is an ophthalmic steroid medication used to treat eye inflammation caused by surgery, infections, allergies, or other conditions.

These eye drops combine tobramycin, an antibacterial, with loteprednol, a corticosteroid. Tobramycin stops the growth and spread of bacterial cells that cause inflammation and discomfort while loteprednol inhibits the inflammatory response in your eyes. Thanks to these actions, Zylet reduces ocular inflammation to relieve discomfort caused by a variety of conditions including infections and allergies.

Dosage and Administration

The dose of Zylet that is prescribed will vary depending on the individual being treated and the factor causing the inflammation. Follow all your healthcare provider’s instructions and read packaging labels to ensure the best results during treatment. Do not use more than recommended for a different length of time than prescribed.

  • Wash hands before and after administration
  • Do not use Zylet while wearing contact lenses
  • Shake the eye drop solution well before each use
  • Most adults instill 1 to 2 drops every 4 to 6 hours
  • For the first 24 to 48 hours of treatment, you can use the eye drops every 1 to 2 hours
  • Frequency of use should gradually decrease as inflammation improves
  • To apply, tilt back your head and gently pull down your lower lid
  • Hold the dropper above your eye, look up and away, and instill a drop into the space created
  • Close your eyes and tip down your head for 2 to 3 minutes
  • Gently press a finger into the inside corner of your eye for a minute to prevent the solution from draining into your tear duct
  • If you apply more than one drop at a time, wait at least 5 minutes in between drops
  • Wait at least 10 minutes after administering Zylet to use any other prescribed eye medications
  • If you wear contact lenses, wait at least 15 minutes before inserting them after use
  • Do not touch the dropper with any surface, including your hands or eyes, to avoid contamination
  • Continue using Zylet for the entire length of time prescribed even if your symptoms improve
  • Store at room temperature away from children and pets
  • Keep the bottle tightly closed and do not let the solution freeze

Side Effects

Zylet may cause you to develop some side effects while reducing inflammation in your eyes. Speak with your healthcare provider to learn more about any symptoms you may encounter when using these eye drops.

Common Zylet side effects may include:

  • Minor burning or stinging sensation when instilling eye drops
  • Increased light sensitivity
  • Watery eyes
  • Puffy eyelids
  • Headache

Serious Side Effects

Some more serious adverse reactions may occur during treatment with Zylet. Stop using this medication and contact your healthcare provider if you develop any of the following side effects:

  • Swollen or red eyes
  • Severe discomfort, crusting, or drainage of eye
  • Cloudy or hazy appearance over your eye or in your vision
  • Severe pain, burning, or stinging when instilling Zylet eye drops

Allergic Reactions

Do not use Zylet eye drops if you are allergic to tobramycin or loteprednol. Stop treatment with Zylet and call your healthcare provider if you notice any of the following signs of an allergic reaction:

  • Hives
  • Trouble breathing
  • Swelling of face, lips, tongue, or throat


  • Do not use Zylet if you have a fungal, viral, or bacterial eye infection.
  • To ensure your safety when using Zylet, tell your healthcare provider if you have any of the following conditions:
    • Glaucoma
    • Cataracts or recent cataract surgery
    • Herpes eye infection
  • Ask your healthcare provider before using Zylet if you are pregnant or breastfeeding. It is unclear whether this medication will harm your unborn or nursing child.
  • Remove contact lenses if you wear them before instilling Zylet. Ask your healthcare provider about the safety of reinserting them after application of this medication. Wait at least 15 minutes before reinserting contacts if your healthcare provider approves of their use.
  • Do not use any other eye medications during treatment unless directed to do so by your healthcare provider. Wait at least 10 minutes after using Zylet to use other eye medications.
  • Do not touch the dropper to any surface, including your hands or eyes, to avoid contamination which can lead to an eye infection.
  • Zylet may cause your vision to blur which could impair your reactions. If this happens, be careful when driving or performing any activities that require alertness and clear vision.
  • Zylet should not interact with other drugs but to help you avoid any drug reactions you should tell your healthcare provider about all the medications you use.
  • Do not administer Zylet to any child younger than 6 years of age without advice from your healthcare provider.


How many days can you use Zylet eye drops?

Zylet eye drops are used to relieve inflammation and irritation caused by a variety of conditions including allergies but are not meant to be used long term. This medication contains a corticosteroid which could lead to the development of glaucoma or other vision problems if used for long periods of time. If you need to use Zylet for more than 10 days, your healthcare provider may monitor the pressure in your eyes.

How many times a day do you use Zylet?

It is recommended that you instill 1 to 2 drops into your affected eye every 4 to 6 hours each day to reduce inflammation. For the first day or two of treatment, your healthcare provider may instruct you to instill your drops every 1 to 2 hours for fast relief. Follow all your healthcare provider’s directions for use to ensure the best therapeutic response during treatment.



Additional information

Brand Name:


Scientific Name:

Tobramycin/ Loteprednol etabonate

Other Names:




Quantities Available:

5mL, 10mL


Eye drops suspension