Safely Buy Anusol Plus Suppository ( Zinc sulfate/pramoxine - non Rx ) from Canada Prescriptions Plus.


Anusol Plus suppository is a rectal medication used to treat hemorrhoids and relieve associated pain and irritation.

The rectal suppository combines zinc, an astringent agent, with pramoxine, an anesthetic drug to provide relief from hemorrhoids. While pramoxine numbs your rectal area to reduce pain, zinc helps reduce inflammation to support the healing process of your hemorrhoids. Thanks to these actions, Anusol Plus suppository relieves irritation and pain caused by hemorrhoids while helping treat your condition.

Dosage and Administration

The administration regimen of Anusol Plus suppositories that is prescribed will vary depending on the individual and severity of the hemorrhoids being treated. Follow all directions of use given by your healthcare provider to ensure the best therapeutic response during treatment. Do not use more than prescribed for longer than recommended without speaking to your healthcare provider.

  • Wash your hands before and after use
  • Wash anal area and gently dry with a soft towel before insertion
  • To use, remove plastic cover from the suppository and then gently insert into your anus
  • Slip the Anusol Plus suppository far enough into your anus so that it won’t slip back out
  • Most patients should insert a suppository at night, in the morning, and after each bowel movement
  • Do not insert using the applicator if this causes more pain
  • Adults should not use more than 5 times a day
  • Do not use Anusol Plus suppositories for longer than 7 consecutive days
  • Store at room temperature out of reach from children and pets

Side Effects

Anusol Plus suppository may cause you to develop side effects while easing pain and inflammation to treat your hemorrhoids. Speak to your healthcare provider to learn more about any symptoms that may occur during treatment.

Common Anusol Plus suppository side effects:

  • Burning, itching, or irritation when applying

Serious Side Effects

Some more serious adverse reactions may occur during treatment with Anusol Plus suppository. Stop using this hemorrhoid medication and contact your healthcare provider right away if you develop any of the following symptoms:

  • Rectal bleeding
  • Change in skin appearance including colour and thickness
  • Skin redness, tenderness, pus or other signs of an infection
  • Signs of a serious infection including fever, or a persistent sore throat

Allergic Reactions

Do not use Anusol Plus suppositories if you are allergic to pramoxine or any of the other suppository ingredients. Stop using this medicine and call your healthcare provider immediately if you notice any of the following signs of an allergic reaction:

  • Rash
  • Itching or swelling of you face, tongue, or throat
  • Severe dizziness
  • Difficulty breathing


  • Anusol Plus suppositories are for insertion into your rectum only and should not be swallowed. If swallowed, call poison control or seek medical attention right away.
  • Do not insert Anusol Plus suppositories using an applicator if the applicator causes more pain in your rectum.
  • Do not use Anusol Plus suppository if you have fungal, viral, or bacterial skin sores.
  • Speak with your healthcare provider if your hemorrhoid symptoms and pain does not improve after 7 days of treatment with Anusol Plus suppositories.
  • Do not use this medication if you are pregnant or breastfeeding because Anusol Plus suppositories could cause harm to your child.
  • To ensure your safety when using Anusol Plus suppository, tell your healthcare provider if you have any of the following:
    • Rectal bleeding or blood in your stools that is not diagnosed as piles
    • Diabetes
    • Vision problems
    • Liver disease
    • Stomach or intestinal problems
  • Some drugs may interact with Anusol Plus suppository and cause adverse reactions. Tell your healthcare provider about all the medications you take, including over the counter medicines, but especially any of the following:
    • Corticosteroids or immunosuppressant drugs
  • Anusol Plus suppository is not approved for use in anyone under the age of 18.

Form and Strength

This hemorrhoid medication is available in suppository form.

  • Anusol Plus suppository strength:
    • 10.75% zinc sulfate/0.25% pramoxine

The 10.75/0.25% strength Anusol Plus suppositories are available in quantities of 12 and 24.


What is the difference between ointments and suppositories?

Both ointment and suppository hemorrhoid treatments contain similar ingredients and function similarly. The Anusol Plus suppository is effective at providing relief from pain, itching, and irritation of internal hemorrhoids found in your rectum. One of the active ingredients offers an analgesic effect to the inside of your rectum. Speak with your healthcare provider to determine the best treatment method for you and your hemorrhoid condition.

How long does it take Anusol Plus suppository to shrink hemorrhoids?

Anusol Plus suppository starts working right away once inserted into your rectum. The medicine may take up to a week to fully relieve and shrink hemorrhoids. Speak with your healthcare provider if your symptoms persist or worsen after 7 days.



Additional information

Brand Name:

Anusol Plus Suppository

Scientific Name:

Zinc sulfate/pramoxine – non Rx

Other Names:

Anusol Plus Suppository



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