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Aricept is a medication used to treat symptoms of dementia caused by Alzheimer’s disease.

Donepezil is an acetylcholinesterase inhibitor that reduces neuroinflammatory responses which affect your brain’s ability to process memory, think, and reason. Thanks to its actions in the brain, Aricept helps improve and reduce dementia in those with Alzheimer’s disease.

This Alzheimer’s medication uses a reversible inhibitor of the acetylcholinesterase enzyme to improve symptoms of dementia with few adverse effects.

Uses and Dosage

The dose of Aricept prescribed will vary depending on the individual being treated. Always follow your doctor’s instructions and read packaging labels carefully.

  • Take once daily in the evening before bed
  • Swallow tablets whole
  • Take with or without food
  • 23mg tablets should be split, crushed, or chewed
  • Patients should start by taking 5mg daily for 4 to 6 weeks before increasing
  • Adults with mild to moderate Alzheimer’s should take 10mg daily
  • Adults with moderate to severe Alzheimer’s should take 23mg daily
  • Doses of 23mg should not be taken before 10mg have been taken for 3 months
  • Do not stop taking Aricept without first consulting your doctor
  • Store at room temperature away from moisture and heat

Side Effects

Aricept may cause some side effects to develop while it inhibits enzymes in your brain to reduce neuroinflammation. Speak with your doctor for more information regarding side effects that you may encounter when taking donepezil.

Common Aricept side effects:

  • Nausea, vomiting, diarrhea
  • Loss of appetite
  • Muscle pain
  • Trouble sleeping
  • Tiredness

Serious Side Effects

Some more serious side effects may occur when taking Aricept. If you notice any of the following symptoms, stop using this medication and seek medical attention:

  • Severe or ongoing vomiting
  • Light-headed feeling, like you might pass out
  • Slow heartbeats
  • Seizure
  • Painful or difficult urination
  • New or worsening trouble breathing
  • Signs of stomach bleeding (severe heartburn or stomach pain, bloody or tarry stools, coughing up blood, vomit that looks like coffee grounds)

Allergic Reaction

Do not take Aricept if you are allergic to donepezil or certain other medications. Consult with your doctor if you are allergic to any medicines before taking. Stop using this medication and call your doctor if you develop signs of an allergic reaction.

Aricept allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


To ensure the safety of taking this medication, tell your doctor if you have any of the following:

  • Heart rhythm disorder
  • History of stomach ulcers
  • An enlarged prostate
  • Trouble urinating
  • Liver or kidney disease
  • Trouble swallowing
  • Seizures or epilepsy
  • Asthma
  • Obstructive pulmonary disease

If you need any form of surgery, tell your surgeon ahead of time that you take Aricept.

Be careful driving or performing any task that requires alertness when taking Aricept because it may impair your thinking or reactions.

Donepezil’s effects on unborn children are unknown; tell your doctor if you are pregnant or plan to become pregnant while using Aricept.

It is not known what effects donepezil may have on nursing babies or whether the drug passes into breast milk or not. Tell your doctor if you breastfeed while taking Aricept and monitor your baby for any unusual symptoms.

Some other medicines may interact with donepezil and cause unwanted side effects. Tell your doctor about all the medications you take, including over the counter medicines, vitamins, and herbal products, but especially non-steroidal anti-inflammatory drugs. These include aspirin, ibuprofen, naproxen, celecoxib, and others.

Form and Strength

This Alzheimer’s medication is available in tablet form.

Aricept tablet strengths:

  • 5mg
  • 10mg
  • 23mg

The 5 and 10mg tablets are both available in quantities of 100 while the 10mg ones are also available in groups of 84; the 23 mg tablets are available in quantities of 30 or 90.


When should I take Aricept?

You can take your dose of Aricept whenever it works best for you, without regard for food. However, it is recommended that you take your daily dose in the evening before going to bed to avoid adverse effects, including drowsiness, during the day.

Can Aricept be used long-term?

Yes, Aricept is generally taken as a long-term treatment for Alzheimer’s related dementia. In fact, high doses of 23mg for severe Alzheimer’s should only be taken after an initial dose of 5mg daily for 4 to 6 weeks followed by 10mg daily for at least 3 months.



Additional information

Brand Name:


Scientific Name:


Other Names:

Aricep 10, Aricep SR, Aricept, Donepezil


5mg, 10mg, 23mg

Quantities Available:

28, 30, 84, 100