Safely Buy Atopica ( Cyclosporine ) from Canada Prescriptions Plus.
We don't sell this generic-version medication.
( Top Brand Option )
Atopica
Prescription Required | Drug Name | Dosage | Quantity | Price | Buy Now |
|---|---|---|---|---|
| Atopica | 25mg | 15 | $51.50 | Add To Cart |
Indications
Atopica is a brand-name medication containing the active ingredient cyclosporine.
Atopica is used in dogs and cats to treat allergic dermatitis, a skin condition caused by contact with an allergen.
Atopica works by suppressing the immune system, which reduces the inflammation associated with allergic dermatitis.
Use and Dosage
The initial dose of Atopica is 5 mg/kg/day (3.3-6.7 mg/kg/day) as a single daily dose for 30 days. Following this initial daily treatment period, the dose of Atopica may be tapered by decreasing the frequency of dosing to every other day or twice weekly, until a minimum frequency is reached which will maintain the desired therapeutic effect.
Atopica should be given at least one hour before or two hours after a meal. If a dose is missed, the next dose should be administered (without doubling) as soon as possible, but dosing should be no more frequent than once daily.
Side Effects
265 dogs were included in the field study safety analysis. One hundred and eleven (111) dogs were treated with a placebo for the first 30 days. For the remainder of the study, all dogs received Atopica capsules.
Fourteen dogs withdrew from the study due to adverse reactions. Four dogs withdrew from the study after vomiting. One dog each withdrew from the study after:
- Diarrhea
- Vomiting, diarrhea, and pruritus
- Vomiting, depression, and lethargy
- Lethargy, anorexia, and hepatitis
- Gingival hyperplasia, lethargy, polyuria/polydipsia, and soft stool
- Seizure
- Sebaceous cyst
- Pruritus
- Erythema
- Otitis externa
Vomiting and diarrhea were the most common adverse reactions occurring during the study. In most cases, signs spontaneously resolved with continued dosing. In other cases, temporary dose modifications (brief interruption in dosing, divided dosing, or administration with a small amount of food) were employed to resolve signs.
Persistent otitis externa, urinary tract infections, anorexia, gingival hyperplasia, lymphadenopathy, and lethargy were the next most frequent adverse events observed. Gingival hyperplasia regressed with dose tapering. Owners of four dogs reported seizures while the dogs were receiving Atopica. In one dog, seizures were the result of a brain tumour diagnosed one month into the study. Another dog experienced seizures before and after the study.
Otitis externa, allergic otitis, or pinna erythema, with or without exudates, commonly accompanies atopy. Many dogs entered the study with otitis externa, which did not resolve without otic treatment. New cases of otitis externa, allergic otitis, or pinna erythema developed while dogs were receiving Atopica. However, the incidence rate was lower with Atopica compared to placebo. A change in the dose frequency was not necessary when new cases occurred.
Cautions
The safety and effectiveness of Atopica have not been established in dogs less than 6 months of age or less than 4 lbs of body weight. Atopica is not for use in breeding dogs or pregnant or lactating bitches.
As with any immunomodulation regimen, exacerbation of sub-clinical neoplastic and infectious conditions may occur.
Gastrointestinal problems and gingival hyperplasia may occur at the initial recommended dose (See Animal Safety).
Atopica may cause elevated levels of serum glucose and should be used with caution in cases with diabetes mellitus. If signs of diabetes mellitus develop following the use of Atopica, consideration should be given to tapering or discontinuing the dose.
Atopica should be used with caution with drugs that affect the P-450 enzyme system.
Since the effect of cyclosporine use on dogs with compromised renal function has not been studied, Atopica should be used with caution in dogs with renal insufficiency.
There have been reports of convulsions in human adult and pediatric patients receiving cyclosporine, particularly in combination with high-dose methylprednisolone (See Animal Safety).
Killed vaccines are recommended for dogs receiving Atopica because the impact of cyclosporine on the immune response to modified live vaccines is unknown.
Form and Strengths
Atopica is available in the following form and strengths:
Atopica Capsule:
- 25 mg
FAQ
How long should I give my pet Atopica for allergic dermatitis?
The duration of treatment may vary depending on the severity of the condition and the individual animal’s response to treatment. Your veterinarian will advise you on the appropriate duration of treatment for your pet.
Can Atopica be given with other medications?
Atopica may interact with certain medications, so it is important to inform your veterinarian about any other medications or supplements your pet is taking before starting Atopica.
What should I do if I miss a dose of Atopica?
If you miss a dose of Atopica, give it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule.
How long does it take for Atopica to start working?
The onset of action for Atopica may vary depending on the individual animal and the severity of the condition. In some cases, it may take several weeks to see an improvement in symptoms.
Is Atopica safe for long-term use in pets?
Long-term use of Atopica may be necessary in some cases, and it is considered safe when used as directed by a veterinarian. However, periodic monitoring of liver and kidney function may be necessary for pets on long-term Atopica therapy.
Resources:
Additional information
Brand Name: |
Atopica |
|---|---|
Scientific Name: |
Cyclosporine |
Other Names: |
Atopica |
Strength(s): |
25mg |
Quantities Available: |
15 |
Formulation: |
Capsule |
