Safely Buy Climara Pro Patch ( Estradiol/Levonorgestrel ) from Canada Prescriptions Plus.

Indications

This medication contains 2 female hormones: estrogen (estradiol) and progestin (levonorgestrel).

Climara Pro Patch is used by women to help reduce certain symptoms of menopause (hot flashes). Symptoms of menopause are caused by the body making less estrogen.

The progestin in this medication helps to reduce the risk of cancer of the uterus which can be caused by using estrogen.

Women who have had their uterus removed do not need the progestin. They should not use this combination of medications. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. This medication may be used by women after menopause to prevent bone loss (osteoporosis).

However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen/progestin treatment.

Use and Dosage

Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Peel off the backing from the patch and apply the patch to a clean, dry area of the lower stomach. Press the patch firmly in place for about 10 seconds to make sure it stays on. Do not apply the patch on the breast or oily, broken, or irritated skin. Avoid applying the patch to areas of the skin where it might be easily rubbed off (such as the waistline). When wearing the patch, do not expose it to the sun for long periods. Use this medication as directed by your doctor. The patch is usually worn for 1 week and then replaced. Follow the dosing schedule carefully.

When replacing your patch, make sure to apply the new patch to a different area. Wait at least 1 week before applying a patch to the same area. Fold the old patch in half with the sticky side together and throw it away in the trash away from children and pets. Do not flush the patch down the toilet.

If a patch falls off, reapply it to a different area. If the patch does not stick completely, then apply a new patch and wear it for the rest of the 7 days. Do not wear 2 patches at the same time.

Use this medication regularly to get the most benefit from it. To help you remember, change the patch on the same day each week. It may help to mark your calendar with a reminder.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Common side effects include:

• Skin rash, redness, or irritation where Climara Pro Patch was applied
• Abdominal pain
• Nausea
• Vomiting
• Bloating
• Headache
• Breast soreness or tenderness
• Weight fluctuations

Rare side effects (talk to your doctor if you experience any of these):

• Swelling in extremities
• Increased thirst
• Frequent urination
• Persistent nausea
• Severe stomach pain
• Vaginal discharge
• Irritation in or around the vagina
• Unusual vaginal bleeding
• Breast lumps
• Memory loss
• Depression
• Anxiety

Very rare side effects (Get IMMEDIATE medical help):

• Blood clotting
• Heart attack
• Stroke
• Muscle or joint pain
• Sweating excessively
• Severe headache
• Weakness or numbness on one side of the body
• Confusion
• Slurred speech
• Vision changes
• Swelling in extremities
• Numbness in extremities
• Trouble breathing
• Coughing blood
• Extreme dizziness

Cautions

Before using this medication, tell your doctor or pharmacist if you are allergic to estradiol or levonorgestrel; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: vaginal bleeding of unknown cause, certain cancers (such as breast cancer, cancer of the uterus/ovaries), blood clots, stroke, heart disease (such as heart attack), liver disease, kidney disease, family medical history (especially breast lumps, cancer, blood clots), family or personal history of a certain swelling disorder (angioedema), blood clotting disorders (such as protein C or protein S deficiency), high blood pressure, diabetes, high blood cholesterol/triglyceride levels, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalance (low or high level of calcium in the blood), a certain hormone problem (hypoparathyroidism), uterus problems (such as fibroids, endometriosis), gallbladder disease, asthma, seizures, migraine headaches, a certain blood disorder (porphyria), mental/mood disorders (such as dementia, depression).

Do not smoke or use tobacco. Estrogens combined with smoking further increase your risk of stroke, blood clots, high blood pressure, and heart attack, especially in women older than 35.

Tell your doctor if you just had or will be having surgery, or if you will be confined to a chair or bed for a long time (such as a long plane flight). These conditions increase your risk of getting blood clots, especially if you are using an estrogen product. You may need to stop this medication for a time or take special precautions.

This medication may cause blotchy, dark areas on your face and skin (melasma). Sunlight may worsen this effect. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.

Form and Strengths

Climara Pro Patch is available in the following form and strengths:

Climara Pro Patch:

• 45/15 mcg

FAQ

Does Climara Pro cause weight gain?

Bloating and modest weight gain may occur while using this medication. However, rapid gain in weight is not normal and not a common side effect. If you gain weight suddenly, you must report it to your physician.

What is the difference between Climara and Climara Pro?

While both transdermal patches contain estradiol, Climara Pro also has levonorgestrel, which is a progestin. These medications are both indicated to manage menopausal symptoms, including hot flashes and vaginal dryness.

Where is the best place to put Climara Pro patch?

You must apply Climara Pro Patch on the lower abdomen or on the buttocks. Do not put it in an area where it can easily be removed, like the waistline.

How do you wean off Climara Pro?

Your physician may lower your dose every two to four weeks to wean you off this medication. You must not discontinue applying this patch abruptly to avoid withdrawal reactions.

Resources:

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021258s003lbl.pdf
2. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=184d3092-7fc6-4375-816b-1ab06bb99cfd
3. https://www.webmd.com/drugs/2/drug-78101/climara-pro-transdermal/details