Neomycin/Polymyxin B/Hydrocortisone

Formulation : Ophthalmic Suspension
Dosage : 3.5/10000U/10mg/mL
Quantity : 7.5mL
Prescription Required
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Cortisporin Ophthalmic Suspension is a medication that contains neomycin, polymyxin B, and hydrocortisone. Cortisporin Ophthalmic Suspension is primarily used for the treatment of certain inflammatory eye conditions that are responsive to corticosteroids and may be associated with bacterial infection or a risk of bacterial infection.

Use and Dosage

Cortisporin Ophthalmic Suspension is available in the form of a suspension.

Use this medicine exactly as directed by your doctor. Follow the instructions provided on the prescription label or as advised by your healthcare provider. Do not use more of it, use it more often, or use it for a longer time than prescribed, as it may increase the chance of side effects.

Cortisporin Ophthalmic Suspension should be used only in the eyes and should not be put into the nose or taken by mouth. If the medication accidentally gets into your eyes or is swallowed, contact your doctor immediately.

The dosage of Cortisporin Ophthalmic Suspension will be determined by your doctor based on your specific condition. Follow the prescribed dosage and schedule. Do not change the dosage without consulting your healthcare provider.

The duration of treatment with Cortisporin Ophthalmic Suspension will depend on the severity of the infection or inflammation and the response to the medication. Complete the full course of treatment as prescribed by your doctor, even if symptoms improve before the treatment is completed.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Serious side effects include:

  • Severe itching, redness, or swelling of your eyes
  • Eye discomfort, crusting or drainage (may be signs of infection)
  • Blurred vision, tunnel vision, eye pain, or seeing halos around lights
  • Pain behind your eyes, sudden vision changes
  • Wound that will not heal

Common side effects of hydrocortisone, neomycin, and polymyxin B may include:

  • Mild eye itching or irritation
  • Eye redness

This is not a complete list of side effects and others may occur. 


  • Some individuals may be allergic to neomycin, polymyxin B, or hydrocortisone. If you have a known allergy to any of these ingredients, avoid using Cortisporin Ophthalmic Suspension. Allergic reactions can range from mild skin irritation to severe reactions. If you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek medical attention immediately.
  • Prolonged or inappropriate use of antibiotics, such as neomycin and polymyxin B, can lead to the development of bacterial resistance. Use cortisporin Ophthalmic Suspension as directed by your healthcare provider and for the prescribed duration of treatment to minimize the risk of bacterial resistance.
  • Cortisporin Ophthalmic Suspension contains hydrocortisone, which is a steroid medication. Prolonged use of steroids can increase the risk of developing fungal infections in the eye. If you notice any signs of a fungal infection, such as increased redness, swelling, or discharge, contact your healthcare provider.
  • If you wear contact lenses, remove them before using Cortisporin Ophthalmic Suspension. Contact lenses should be kept out of the eye during treatment and for some time as advised by your healthcare provider. Contact lenses can interfere with the effectiveness of the medication and may increase the risk of adverse reactions.
  • The use of Cortisporin Ophthalmic Suspension during pregnancy and or during breastfeeding should be discussed with the healthcare providers. Weigh the potential benefits against the potential risks to the developing fetus or nursing infant. Consultation with a healthcare provider is essential to make an informed decision.

Forms and Strengths

Cortisporin Ophthalmic Suspension is available in the following forms and strengths:

  • Neomycin/Polymyxin B/Hydrocortisone Ophthalmic Suspension:
    • 3.5/10000U/10mg/mL


What happens if I miss a dose?

Use the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

An overdose of hydrocortisone, neomycin, and polymyxin B ophthalmic is not expected to be dangerous. Seek emergency medical attention if anyone has accidentally swallowed the medication.

What should I avoid while using hydrocortisone, neomycin, and polymyxin B?

Do not share this medicine with another person, even if they have the same symptoms you have.

What other drugs will affect hydrocortisone, neomycin, and polymyxin B?

Medicine used in the eyes is not likely to be affected by other drugs you use. However, many drugs can interact with each other.



Additional information

Brand Name:

Cortisporin Ophthalmic Suspension

Scientific Name:

Neomycin/Polymyxin B/Hydrocortisone

Other Names:

Neomycin/Polymyxin B/Hydrocortisone



Quantities Available:



Ophthalmic Suspension