Safely Buy Depo Medrol Injection ( Methylprednisolone acetate ) from Canada Prescriptions Plus.

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Depo Medrol Injection

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Formulation : Vial
Drug Name Dosage Quantity Price Buy Now
Depo Medrol Injection 20mg/mL 5mL $33.30 Add To Cart
Depo Medrol Injection 40mg/mL 2mL $44.30 Add To Cart
Depo Medrol Injection 80mg/mL 5mL $82.20 Add To Cart
Depo Medrol Injection
Dosage: 20mg/mL
Quantity: 5mL
Price: $33.30
Depo Medrol Injection
Dosage: 40mg/mL
Quantity: 2mL
Price: $44.30
Depo Medrol Injection
Dosage: 80mg/mL
Quantity: 5mL
Price: $82.20


Depo-medrol injection is used to treat inflammation in conditions like rheumatoid arthritis, lupus, and allergic reactions. The medication is injected directly into affected tissues.

Methylprednisolone is the active ingredient that works on the immune system to relieve swelling, redness, and itching.

Depo medrol injection is a type of corticosteroid injection that is used to reduce inflammation and treat a variety of inflammatory conditions. It helps by modulating the immune response.

Use and Dosage

Shake this medication well before using it. This medication is usually injected into a joint as directed by your doctor. Methylprednisolone may also be injected into a muscle or abnormal skin tissue. Follow your doctor’s directions carefully. The dosage is based on your medical condition and response to treatment. Do not increase your dose or use this drug more often than prescribed without consulting your doctor. Your condition will not improve any faster, and your risk of side effects will increase.

If you are using this medication at home, learn all preparation and usage instructions from your health care professional. This medication should appear milky white. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.

If this medication is injected into a joint, be careful how much pressure you put on that joint, even if it is feeling better. Ask your doctor how much you can move/use the joint while it is healing.

Do not stop using this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

If you suddenly stop using this medication, you may have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, and dizziness). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used methylprednisolone for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal. See also the Precautions section.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Depo-Medrol may cause serious side effects:

  • Blurred vision, tunnel vision, eye pain, or seeing halos around lights
  • Shortness of breath (even with mild exertion), swelling, or rapid weight gain
  • Severe depression, changes in personality, unusual thoughts, or behavior
  • New or unusual pain in an arm or leg or your back
  • Severe pain in your upper stomach spreading to your back, nausea, and vomiting
  • Bloody or tarry stools, coughing up blood, or vomit that looks like coffee grounds
  • A seizure (convulsions)
  • Low potassium–leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, or muscle weakness or limp feeling
  • Depo-Medrol can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using Depo-Medrol.

Common side effects of Depo-Medrol may include:

  • Weight gain (especially in your face or your upper back and torso)
  • Slow wound healing
  • Muscle pain or weakness
  • Thinning skin or increased sweating
  • Stomach discomfort or bloating
  • Headache
  • Changes in your menstrual periods

This is not a complete list of side effects and others may occur.


Before using methylprednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye diseases (such as cataracts, glaucoma, herpes infection of the eye), heart problems (such as congestive heart failure, recent heart attack), high blood pressure, current/ past infections (such as those caused by tuberculosis, threadworm, herpes, fungus), kidney disease, liver disease, mental/mood conditions (such as psychosis, anxiety, depression), stomach/intestinal problems (such as diverticulitis, ulcer, ulcerative colitis), seizures.

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you dizzier. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis).

This medicine may cause stomach bleeding. Daily use of alcohol while using this medicine may increase your risk of stomach bleeding. Limit alcoholic beverages. Consult your doctor or pharmacist for more information.

Tell your healthcare professional that you are using methylprednisolone before having any immunizations, vaccinations, or skin tests. Avoid contact with people who have recently received live vaccines (such as a flu vaccine inhaled through the nose).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress. Before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication. See also the Medical Alert section.

Older adults may be more sensitive to the side effects of this drug, especially bone loss/pain, stomach/intestinal bleeding, and mental/mood changes (such as confusion).

This medication may slow down a child’s growth if used for a long time. Consult the doctor or pharmacist for more details. See the doctor regularly so your child’s height and growth can be checked.

During pregnancy, this medication should be used only when needed. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who use this medication for a long-time during pregnancy may have hormone problems. Tell your doctor right away if you notice symptoms such as nausea/vomiting that does not stop, severe diarrhea, or weakness in your newborn.

This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.

Form and Strengths

The depo-medrol injection is available in the following form and strengths:

Depo-medrol injection Vial:

  • 20 mg/ml


What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Depo-Medrol.

What happens if I overdose?

Seek emergency medical attention.

What should I avoid while receiving Depo-Medrol?

Do not receive a “live” vaccine while using Depo-Medrol. Live vaccines include measles, mumps, and rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using Depo-Medrol.



Additional information

Brand Name:

Depo Medrol Injection

Scientific Name:

Methylprednisolone acetate

Other Names:

Depo Medrol Injection


20mg/mL, 40mg/mL, 80mg/mL

Quantities Available:

2mL, 5mL