Safely Buy Depo Provera Injection ( Medroxyprogesterone ) from Canada Prescriptions Plus.


Depo-Provera injection is a type of contraceptive injection that contains the hormone progestin, which is administered once every three months to prevent pregnancy.

Depo-Provera injection is a safe, effective, and convenient birth control method that is given by injection in the arm or buttocks.

If you have any concerns or specific questions about Depo-Provera, it is recommended to consult with a healthcare provider.

Use and Dosage

You can get a version of Depo-Provera that you inject at home. This version of the shot is only subcutaneous, which means it goes into your skin instead of deep into your muscle.

Experts call the at-home shot Depo-sub Q Provera 104. It is a prefilled, single-use syringe with a smaller needle than the one your doctor uses, so it may hurt less. It uses a lower dose of progestin than the 400 milligrams in the dose from your doctor. You will need to give yourself a shot in the thigh or belly every 12 weeks for it to work.

Your doctor can show you (in person or through telemedicine) how to inject yourself and safely throw away sharp tools after your shot. Follow their guidance. At-home Depo-Provera is safe to use. It is not likely, but if you notice a reaction at the injection site, let your doctor know.

You may notice a lump, dimple, or dent at the reaction site. You may also see redness, bruising, blistering, or itchiness.

If you think something is not right, call your doctor right away. They can help clear up confusion or guide you while you use Depo-Provera at home.

Both the original and at-home versions are 99% effective at preventing pregnancy if you get it every 3 months, as directed. But because that is not always possible, typical effectiveness is around 94%. That means for every 100 women who get the shot, about 6 will have an accidental pregnancy.

Side Effects

These are the same for both the original version and the at-home one. You might notice:

  • Uneven menstrual periods or no periods at all
  • Headaches
  • Nervousness
  • Depression
  • Dizziness
  • Acne
  • Changes in appetite
  • Weight gain
  • Unwanted facial and body hair
  • Hair loss
  • Loss of bone mineral density
  • Belly pain
  • Bloating
  • Breakthrough bleeding
  • Fatigue
  • Less interest in sex
  • Weakness
  • Allergic reaction (this is rare)

Changes to your menstrual cycle are the most common side effects. After a year of use, about 50% of women will stop getting their periods. If this happens to you, your period should come back when you stop getting the shots.

Long-term use of Depo-Provera may cause you to lose bone mineral density, which makes you more likely to get osteoporosis. Your chances are higher if you have taken the shot for longer than 2 years, especially if osteoporosis runs in your family if you drink a lot, if you smoke, or if you have other risk factors for the condition.


Some cautions to keep in mind when using Depo-Provera Contraceptive Injection (medroxyprogesterone) are:

  • Loss of bone mineral density: Women who use Depo-Provera CI may experience a significant loss of bone mineral density.
  • Delayed return of ovulation or fertility: The median time to ovulation was 10 months after the last injection.
  • Cardiovascular disorders: Discontinue estrogen-containing contraceptives before starting Depo-Provera in women with uncontrolled hypertension or a history of thromboembolic or cerebrovascular disorders.
  • Depression: Women with a history of depression should be observed because Depo-Provera CI may worsen the condition.
  • Elevated blood pressure: Women with a history of hypertension should be observed closely and their blood pressure should be monitored regularly.
  • Diabetes mellitus: Women with diabetes should be observed closely as their glucose tolerance may be altered while using Depo-Provera CI.
  • Liver and/or renal dysfunction: Women with abnormal liver function test results or renal dysfunction should be observed.
  • Chronic use: Depo-Provera CI is not recommended for long-term use (beyond 2 years) unless other options are not adequate.
  • Interaction with other drugs: Depo-Provera CI may interact with some medications, such as anticonvulsants, and decrease their effectiveness.

Form and Strengths

Depo Provera Injection is available in the following form and strengths:

  • Depo Provera Injection Vial:
    • 150 mg/ml


How often do I need to get the injection?

The injection is given once every 12 weeks or 3 months.

Is Depo-Provera an effective contraceptive?

Yes, Depo-Provera is highly effective when used correctly, with a failure rate of less than one in 100 users per year.

Can I use Depo-Provera if I am breastfeeding?

Yes, Depo-Provera can be used while breastfeeding. It does not affect the quality or quantity of breast milk, but it may decrease the amount of time between feedings.

Is Depo-Provera reversible?

Yes, the effects of Depo-Provera are reversible, but it may take up to 10 months after stopping the injections for fertility to return.

What should I do if I miss a scheduled injection?

If you miss a scheduled injection, you should return for the next injection as soon as possible. You should also use a backup form of contraception, such as condoms until you receive the next injection.

Are there any risks associated with using Depo-Provera?

Like any medication, Depo-Provera has some potential risks. Long-term use may reduce bone mineral density, increasing the risk of osteoporosis. It may also slightly increase the risk of breast cancer in younger women who use it for more than five years. Users with a history of blood clots, liver problems, or unexplained vaginal bleeding should not use Depo-Provera.



Additional information

Brand Name:

Depo Provera Injection

Scientific Name:


Other Names:

Depo Provera Injection



Quantities Available:

1mL, 2mL