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Fosamax (alendronate sodium) is a medication used to treat and prevent osteoporosis in adults. Fosamax is a bisphosphonate that works by slowing the process of bone loss and increasing bone mass.

Use and Dosage

Take Fosamax exactly as prescribed by your doctor. Fosamax is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Fosamax first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water. Do not crush, chew, or suck on a Fosamax tablet. Swallow the tablet whole.

Side Effects

Common Side Effects Include:

  • Heartburn, upset stomach
  • Stomach pain, nausea
  • Diarrhea, constipation
  • Headaches
  • Bone pain, muscle, or joint pain

Serious side effects tend to be rarer, but you should stop taking this medicine and notify your doctor immediately if you notice any of the following:

Esophageal or stomach ulcers:

  • Chest pain
  • Heartburn
  • Difficulty or pain when swallowing
  • Under the ribcage or in the back, you may experience discomfort or burning
  • Severe heartburn
  • Burning pain in your upper stomach
  • Coughing up blood
  • Blood or black stools


You should not take Fosamax if you are allergic to alendronate, or if you have:

  • Low levels of calcium in your blood (hypocalcemia)
  • Problems with the muscles in your esophagus (the tube that connects your mouth and stomach)

Do not take Fosamax if you cannot sit upright or stand for at least 30 minutes. Fosamax can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

  • Trouble swallowing
  • Problems with your stomach or digestion
  • Low levels of calcium in your blood
  • A dental problem (you may need a dental exam before you begin taking Fosamax)
  • Kidney disease
  • Any condition that makes it hard for your body to absorb nutrients from food (malabsorption)

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Fosamax, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.

Fosamax has also been reported to cause fractures, or broken bones, in the leg’s large bones. Tell your doctor if you have any leg or groin pain while using Fosamax. Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Fosamax will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

It is not known whether alendronate passes into breast milk or if it could harm a nursing baby. Ask your doctor about any risks.

Form and Strengths

Fosamax is available in the following form and strengths:

  • Fosamax Tablet:
    • 70mg
  • Alendronate Tablet:
    • 10mg
    • 35mg
    • 70mg


What is Osteoporosis?

Osteoporosis is a condition that affects bones. Contrary to what bones are often thought of the skeleton is made up of organic tissues comprised of living cells.

Who should not take Fosamax?

Fosamax can have side effects in some cases that have dangerous implications for those with specific health conditions.



Additional information

Brand Name:


Scientific Name:


Other Names:

Alendronate, Alendronic Acid, Fosamax, Osteofos


10mg, 35mg, 70mg

Quantities Available:

4, 12, 100