Safely Buy Hyalgan ( Sodium Hyaluronate ) from Canada Prescriptions Plus.


Hyalgan is a medication used for the treatment of pain in knee osteoarthritis. It is administered by injection into the knee joint and contains sodium hyaluronate, which acts as a replacement for synovial fluid in the joint.

Hyalgan works by acting as a lubricant and shock absorber in the joint and is typically used in patients who have not responded to conservative treatments such as physical therapy or nonsteroidal anti-inflammatory drugs.

Use and Dosage

Read the Patient Information Leaflet provided by your health care professional before you start using hyaluronate each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Your doctor will give this medication by injection into the affected joint, usually once a week. Skin disinfectants that contain ammonium salts (such as benzalkonium chloride) should not be used to prepare the injection site. Your doctor may need to remove extra fluid from the joint before injecting the medicine. Dosage is based on your medical condition and response to treatment.

Hyaluronate should not be injected into a vein or artery because increased side effects may occur.

After receiving an injection of hyaluronate, you should avoid any activities that put stress on your knee (such as jogging, tennis, heavy lifting, or standing on your feet for more than an hour) for 48 hours.

Also, after the injection, you may experience increased pain and swelling in the knee at first. If the pain or swelling continues or worsens, talk to your doctor promptly.

It is important to have this medication injected on schedule. It may take up to 3 injections before the full benefits of this medication occur.

Tell your doctor if your condition lasts or gets worse.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Serious side effects:

  • Severe pain or swelling around the knee after the injection

Common side effects of Hyalgan may include:

  • Warmth, pain, redness, stiffness, bruising, or puffiness where the medicine was injected
  • Nausea, stomach pain
  • Trouble walking
  • Swelling in your hands or feet
  • Back pain, joint pain, muscle pain
  • Numbness or tingly feeling
  • Headache, dizziness
  • Runny or stuffy nose, sneezing, sore throat

This is not a complete list of side effects and others may occur.


Before using hyaluronate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. For some brands, also tell your doctor or pharmacist if you are allergic to bird proteins, feathers, or egg products. This product may contain inactive ingredients (such as latex found in the rubber syringe cap of some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: knee joint infections, skin infections/problems in the area around the injection site, and circulation problems in the legs.

During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Form and Strengths

Hyalgan is available in the following form and strengths:

  • Hyalgan Injection:
    • 20mg/2mL


What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Hyalgan.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving Hyalgan?

For at least 48 hours after your injection, avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis. Also, avoid weight-bearing activity or standing for longer than 1 hour at a time. Ask your doctor how long to wait before you resume these activities.



Additional information

Brand Name:


Scientific Name:

Sodium Hyaluronate

Other Names:




Quantities Available:

1syr, 3syr