Safely Buy Protelos from Canada Prescriptions Plus.
Indications
Protelos is a medication that was used to treat osteoporosis in postmenopausal women and adult men at high risk of fracture. It contained the active substance strontium ranelate.
The main benefit of Protelos was its ability to reduce the risk of fractures. In a study, it was found that Protelos reduced the risk of new breaks in the spine by 41% over three years.
Use and Dosage
Treatment should only be started by a doctor with experience in treating osteoporosis. As there has been some data showing an increased risk of heart attack with Protelos, the decision to prescribe Protelos should take into account the patient’s heart risk.
Protelos is taken as one sachet once a day. The contents of the sachet are added and mixed into a glass of water to form a suspension, which is drunk just after being prepared. Protelos should be taken at least two hours after food, milk, milk products or calcium supplements, preferably at bedtime. Protelos is intended for long-term use. Patients should also receive calcium or vitamin D supplements if they are not getting enough from their diet.
Side Effects
When taken by mouth: Strontium is LIKELY SAFE when taken in amounts found in food. The typical diet includes 0.5-1.5 mg of strontium per day. Taking a prescription form of strontium, known as strontium ranelate, for up to 10 years is POSSIBLY SAFE. Strontium ranelate might cause side effects such as stomach pain, diarrhea, and headache in some people. This form of strontium is not available in the U.S.
Taking very high doses of strontium by mouth is POSSIBLY UNSAFE. High doses of strontium might damage the bones. There is not enough reliable information to know if the form of strontium typically contained in dietary supplements (strontium chloride) is safe or what the side effects might be.
When given by IV: The prescription form of strontium known as strontium-89 chloride is LIKELY SAFE when given intravenously (by IV) under the supervision of a healthcare provider.
When applied to the teeth: Toothpastes (Sensodyne-SC) that contain strontium are LIKELY SAFE and have received safety approval from the U.S. Food and Drug Administration (FDA).
Cautions
- Pregnancy and breastfeeding: Strontium is LIKELY SAFE to take in food amounts or use in toothpaste (Sensodyne-SC) when pregnant or breastfeeding. There is not enough reliable information to know if taking strontium by mouth in larger amounts is safe when pregnant or breastfeeding. Stay on the safe side and stick to food amounts. A specific prescription form of strontium, strontium-89, is LIKELY UNSAFE during pregnancy and breastfeeding. It is a radioactive material that might harm the fetus. It may also pass into breast milk and could harm a nursing infant.
- Heart disease: Do not use strontium if you have high blood pressure or heart disease.
- Cerebrovascular disease (stroke): Do not use strontium if you have a history of stroke or poor circulation to the brain.
- Paget’s disease (a bone disease): Use strontium with caution. The bones of people with Paget’s disease seem to take up more strontium than normal. It is not known how important this finding is for health.
- Peripheral arterial disease (decreased blood flow through veins): Do not use strontium if you have peripheral arterial disease.
- Kidney problems: Strontium is eliminated by the kidneys and can build up in people with poor kidney function. Use strontium supplements with caution if you have kidney disease. Strontium ranelate should not be used if kidney disease is advanced.
- Blood clotting disorders: Strontium ranelate is associated with a small increased risk of blood clots. There is concern that strontium might be more likely to cause blood clots in people with blood clotting disorders or those at high risk of blood clotting. It is best not to use strontium if you have a clotting disorder.
Forms and Strengths
Protelos is available in the following forms and strengths:
- Protelos Granules:
- 2 g
FAQ
Why has Protelos been approved?
The CHMP decided that Protelos’s benefits are greater than its risks and recommended that it be given marketing authorization.
What measures are being taken to ensure the safe and effective use of Protelos?
A risk management plan has been developed to ensure that Protelos is used as safely as possible. Based on this plan, safety information has been included in the summary of product characteristics and the package leaflet for Protelos, including the appropriate precautions to be followed by healthcare professionals and patients.
What is the risk associated with Protelos?
The most common side effects with Protelos (which may affect more than 1 in 10 people) are hypersensitivity (allergic) skin reactions (rash, itching, urticaria or itchy rash, and swelling beneath the skin known as angioedema) and pain affecting muscles, bones, and joints. For the full list of all side effects reported with Protelos, see the package leaflet.
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Additional information
Quantities Available: |
28 |
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Formulation: |
granules |
