Safely Buy Pyrazinamide ( Pyrazinamide ) from Canada Prescriptions Plus.

We don't sell this brand-version medication.

( Affordable Generic Alternatives )


Prescription Required
Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Pyrazinamide 500mg 100 $136.35 Add To Cart
Dosage: 500mg
Quantity: 100
Price: $136.35


Pyrazinamide is an antibiotic medication used to treat tuberculosis in children and adults.

Pyrazinamide is an antimicrobial drug that kills drug-resistant bacteria in tuberculosis lung lesions by inhibiting bacterial biosynthesis. These actions help the medication reduce treatment duration by three months without increasing liver damage.

This tuberculosis medication is an effective addition to treatment that improves symptoms and kills bacteria faster than treatment without it. Pyrazinamide is beneficial in cases with drug-resistant tuberculosis and can reduce treatment duration from 12 months down to 9 or 6 months.

Uses and Dosage

The dose of Pyrazinamide that is prescribed will vary depending on the individual. Follow your doctor’s instructions and read packaging labels carefully to ensure the best therapeutic results.

  • Swallow tablet whole
  • Pyrazinamide should be used with other medicines and not alone
  • Do not use more or less of this medication for longer than prescribed
  • You may only need to take pyrazinamide for the first 2 months of your treatment
  • Pyrazinamide is usually taken once a day but may be prescribed for 2 times a week
  • Adults tend to take 15 to 30mg/kg once a day
  • Adults should not take more than 3 grams a day
  • Some may take 50 to 70mg/kg of lean body weight twice weekly
  • Patients older than 60 should take 10mg/kg and should not exceed daily doses of 750mg
  • Symptoms may improve before your infection is completely treated, use your medications for the entire length of time prescribed
  • Tell any doctor that treats you that you take pyrazinamide because it can affect test results
  • Store at room temperature away from children and pets

Side Effects

Pyrazinamide may cause some side effects to develop while killing harmful bacteria in your lungs to treat tuberculosis. Speak with your doctor for more information regarding any symptoms that you may encounter when using pyrazinamide.

Common pyrazinamide side effects:

  • Joint or muscle pain
  • Nausea, vomiting
  • Loss of appetite

Serious Side Effects

Some more serious adverse effects may occur when taking pyrazinamide. Stop using this tuberculosis medication and contact your doctor if you develop any of the following symptoms:

  • Fever
  • Joint pain or swelling
  • Easy bruising or bleeding
  • Symptoms of gout (joint pain, stiffness, redness, or swelling)
  • Liver problems (nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-coloured stools, jaundice)

Allergic Reactions

Do not use this medication if you are allergic to pyrazinamide. If you develop signs of an allergic reaction, stop using this tuberculosis medication and call your doctor.

Pyrazinamide allergy symptoms may include:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat


Pyrazinamide is designed to be taken in combination with other antituberculosis medications and should not be taken on its own.

Do not use pyrazinamide if you have gout or severe liver disease.

To ensure your safety when taking pyrazinamide, tell your doctor if you have any of the following:

  • HIV or AIDS
  • Gout
  • Liver disease
  • Diabetes
  • If you drink large quantities of alcohol

Your doctor may check your liver enzymes and uric acid levels before prescribing treatment to ensure that pyrazinamide is safe for you to take.

Tell your doctor if you are pregnant or breastfeeding before using this medication. It is unclear whether pyrazinamide will harm an unborn or nursing child.

Some other drugs may interact with pyrazinamide and cause adverse reactions. Tell your doctor about all the medications that you take, including over the counter medicines, vitamins, and herbal products.

Form and Strength

This tuberculosis medication is available in tablet form.

Pyrazinamide tablet strength:

  • 500mg

The 500mg pyrazinamide tablets are available in quantities of 100.


What should be monitored when taking pyrazinamide?

Your doctor should test your liver enzymes and uric acid levels before prescribing pyrazinamide and regularly during treatment. Pyrazinamide and other antituberculosis medications may cause harm to your liver, although this medication has shown to improve tuberculosis without severely increasing your risk of hepatoxicity.

What is the main adverse effect of pyrazinamide?

The most common side effects reported from pyrazinamide use include nausea, vomiting, loss of appetite, and mild muscle or joint pain. These are often mild and tolerable reactions but contact your doctor for guidance if any effects persist or worsen.



Additional information

Brand Name:


Scientific Name:


Other Names:




Quantities Available: