Safely Buy Xerese ( Acyclovir/Hydrocortisone ) from Canada Prescriptions Plus.

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Prescription Required
Formulation : Cream
Drug Name Dosage Quantity Price Buy Now
Xerese 5/1% 5g $64.30 Add To Cart
Xerese 5/1% 10g $108.40 Add To Cart
Xerese 5/1% 15g $151.20 Add To Cart
Dosage: 5/1%
Quantity: 5g
Price: $64.30
Dosage: 5/1%
Quantity: 10g
Price: $108.40
Dosage: 5/1%
Quantity: 15g
Price: $151.20


This medication contains 2 ingredients: acyclovir and hydrocortisone.

Xerese is used to treat cold sores/fever blisters caused by a virus (herpes simplex).

Acyclovir is an antiviral medication that works by stopping the growth of the virus. Hydrocortisone is a corticosteroid that helps relieve itching, pain, and burning symptoms. This medication can speed up the healing of cold sores, but it does not cure herpes or prevent passing the infection to someone else. It does not prevent cold sores from returning.

Use and Dosage

Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Use this medication at the first sign of a cold sore. Wash your hands with soap and water before and after applying this medication. Clean and dry the affected area before applying the medication. Apply a thin layer on the affected area as directed by your doctor, usually 5 times a day (every 3 to 4 hours) for 5 days. Apply enough cream to cover all affected areas. Do not rub the area because it may spread to other areas around your mouth or make your cold sore worse. Do not apply other skin products (including make-up, sunscreen, or lip balm) or cover the affected area with a bandage. To prevent washing off the medication, do not bathe, shower, or swim for 30 minutes after application.

Do not apply this medication in the eyes or nose, inside the mouth, or on the genitals.

Cold sores (herpes) can spread easily. Acyclovir/hydrocortisone cream does not prevent the spread of herpes. Avoid sharing eating utensils, cups, razors, or towels during an outbreak. Also, try not to touch the cold sore (including kissing), and wash your hands if you do touch the cold sore.

Use this product regularly to get the most benefit from it. Tell your doctor if your condition lasts or gets worse after 2 weeks.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to Xerese cream: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have severe burning, stinging, or irritation of treated skin.

Common Xerese side effects may include:

  • Mild burning or tingling after applying the medicine
  • Skin dryness or flaking
  • Swelling
  • Skin redness or discoloration

This is not a complete list of side effects and others may occur.


  • Before using this product, tell your doctor or pharmacist if you are allergic to acyclovir or hydrocortisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • Before using this medication, tell your doctor or pharmacist your medical history.
  • Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
  • Tell your doctor if you are pregnant before using this medication.
  • This product may pass into breast milk in small amounts. However, it is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Forms and Strengths

Xerese is available in the following forms and strengths:

  • Xerese Cream:
    • 5/1 %


What happens if I miss a dose?

Apply the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

An overdose of Xerese cream is unlikely to occur.

What should I avoid while using Xerese Cream?

Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent the spread of infection.

Do not share this medicine with another person, even if they have the same symptoms you have.

Avoid getting this medicine in your eyes, nose, mouth, or vagina.



Additional information

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Quantities Available:

5g, 10g, 15g